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Congenital factor VII deficiency
The Indian Journal of Pediatrics, 2004A 1(1/2)-month-old baby with seizures, lethargy and refusal of feeds was diagnosed to have intracranial hemorrhage due to factor VII deficiency. MRI also demonstrated the unusual presence of a hemorrhagic infarct. The case underscores the importance of carrying out neuroimaging and appropriate hematological studies even in the absence of obvious ...
Mamta N. Muranjan+3 more
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Congenital deficiency of factor VII
The Indian Journal of Pediatrics, 1996A case of congenital factor VII deficiency in a five-year-old child is reported. The patient, born of a non-consanguineous marriage, presented with repeated bouts of epistaxis since childhood. The prothrombin time (PT) was markedly prolonged with a normal bleeding time (BT), partial thromboplastin time with Kaolin (PTTK) and platelet count. The patient
Satendra Sharma+4 more
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Factor VII deficiency and pregnancy
International Journal of Gynecology & Obstetrics, 1989Hereditary factor VII deficiency is very rare in pregnancy (one in 500,000). However, obstetricians should consider this diagnosis whenever the prothrombin time is prolonged while the activated partial thromboplastin time is normal. The factor VII level increases in normal pregnancy, but the effect of pregnancy upon the factor VII level in deficient ...
JS Krauss, Hossam E Fadel
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Thrombosis in inherited factor VII deficiency
Journal of Thrombosis and Haemostasis, 2003Thrombosis in congenital factor (F) VII deficiency was investigated through extensive phenotypic and molecular-genetic studies. Patients with a history of thrombosis among 514 entries in the FVII Deficiency Study Group database were evaluated. Thrombotic events were arterial in one case, disseminated intravascular coagulation in another and venous in ...
MARIANI G+12 more
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Acquired and Isolated Deficiencies in Factor VII
Clinical Laboratory, 2022Acquired and isolated deficiencies in FVII are exceptional. They have mainly been reported during states of severe sepsis by the presence of proteases destroying the factor or neoplastic pathologies by the presence of an inhibitor. Consequently, very few cases have been published.We report two cases of isolated and acquired deficiency of factor VII due
F Z, Alouhmy+3 more
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Hobby-Induced Factor VII Deficiency
Pathophysiology of Haemostasis and Thrombosis, 1972Hemorrhagíc tendency and granulocytopenia due to prolonged contact with trichloroethylene and toluene are described in a boy whose hobby was model air-plane assembly. The hemostatic defects found were hypoproconvertinemia, moderate hypofibrinogenemia, and increased capillary fragility.
A de Vries+3 more
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Acquired Factor VII deficiency – a rare but important consideration
Scottish Medical Journal, 2019Introduction Isolated acquired Factor VII deficiency is a rare coagulation disorder which is independent of vitamin K deficiency. The exact pathophysiological basis of this condition is unclear.
M. H. Zaidi, A. Stanley, Mohammed Khan
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A case of heterozygous factor VII deficiency in pregnancy
Journal of Obstetrics and Gynaecology Research, 2019Factor VII deficiency is a rare inherited disorder of coagulation. The prevalence of this disorder is estimated at roughly 1:500,000 for homozygotes and 1:350 in heterozygotes (Hunault and Bauer 20...
Jamal Hasoon, J. Rivers
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2018
This chapter outlines the pathophysiology, clinical presentation, inheritance, and incidence of factor VII deficiency. The chapter describes the interaction with pregnancy and discusses the medical and anesthetic management of pregnant women with factor VII deficiency, including treatment of acute hemorrhage.
Joanne Douglas, James P. R. Brown
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This chapter outlines the pathophysiology, clinical presentation, inheritance, and incidence of factor VII deficiency. The chapter describes the interaction with pregnancy and discusses the medical and anesthetic management of pregnant women with factor VII deficiency, including treatment of acute hemorrhage.
Joanne Douglas, James P. R. Brown
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LIVER TRANSPLANTATION FOR FACTOR VII DEFICIENCY
Transplantation, 2001Factor VII deficiency is a serious, potentially lethal disorder of blood coagulation caused by a defect in hepatic factor VII synthesis. We report two children, sisters, both with severe, recurrent hemorrhagic complications from factor VII deficiency, successfully treated with orthotopic liver transplantation.
David Levi+4 more
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