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Congenital factor VII deficiency

The Indian Journal of Pediatrics, 2004
A 1(1/2)-month-old baby with seizures, lethargy and refusal of feeds was diagnosed to have intracranial hemorrhage due to factor VII deficiency. MRI also demonstrated the unusual presence of a hemorrhagic infarct. The case underscores the importance of carrying out neuroimaging and appropriate hematological studies even in the absence of obvious ...
Mamta N. Muranjan   +3 more
openaire   +3 more sources

Congenital deficiency of factor VII

The Indian Journal of Pediatrics, 1996
A case of congenital factor VII deficiency in a five-year-old child is reported. The patient, born of a non-consanguineous marriage, presented with repeated bouts of epistaxis since childhood. The prothrombin time (PT) was markedly prolonged with a normal bleeding time (BT), partial thromboplastin time with Kaolin (PTTK) and platelet count. The patient
Satendra Sharma   +4 more
openaire   +3 more sources

Factor VII deficiency and pregnancy

International Journal of Gynecology & Obstetrics, 1989
Hereditary factor VII deficiency is very rare in pregnancy (one in 500,000). However, obstetricians should consider this diagnosis whenever the prothrombin time is prolonged while the activated partial thromboplastin time is normal. The factor VII level increases in normal pregnancy, but the effect of pregnancy upon the factor VII level in deficient ...
JS Krauss, Hossam E Fadel
openaire   +3 more sources

Thrombosis in inherited factor VII deficiency

Journal of Thrombosis and Haemostasis, 2003
Thrombosis in congenital factor (F) VII deficiency was investigated through extensive phenotypic and molecular-genetic studies. Patients with a history of thrombosis among 514 entries in the FVII Deficiency Study Group database were evaluated. Thrombotic events were arterial in one case, disseminated intravascular coagulation in another and venous in ...
MARIANI G   +12 more
openaire   +4 more sources

Acquired and Isolated Deficiencies in Factor VII

Clinical Laboratory, 2022
Acquired and isolated deficiencies in FVII are exceptional. They have mainly been reported during states of severe sepsis by the presence of proteases destroying the factor or neoplastic pathologies by the presence of an inhibitor. Consequently, very few cases have been published.We report two cases of isolated and acquired deficiency of factor VII due
F Z, Alouhmy   +3 more
openaire   +2 more sources

Hobby-Induced Factor VII Deficiency

Pathophysiology of Haemostasis and Thrombosis, 1972
Hemorrhagíc tendency and granulocytopenia due to prolonged contact with trichloroethylene and toluene are described in a boy whose hobby was model air-plane assembly. The hemostatic defects found were hypoproconvertinemia, moderate hypofibrinogenemia, and increased capillary fragility.
A de Vries   +3 more
openaire   +2 more sources

Acquired Factor VII deficiency – a rare but important consideration

Scottish Medical Journal, 2019
Introduction Isolated acquired Factor VII deficiency is a rare coagulation disorder which is independent of vitamin K deficiency. The exact pathophysiological basis of this condition is unclear.
M. H. Zaidi, A. Stanley, Mohammed Khan
semanticscholar   +1 more source

A case of heterozygous factor VII deficiency in pregnancy

Journal of Obstetrics and Gynaecology Research, 2019
Factor VII deficiency is a rare inherited disorder of coagulation. The prevalence of this disorder is estimated at roughly 1:500,000 for homozygotes and 1:350 in heterozygotes (Hunault and Bauer 20...
Jamal Hasoon, J. Rivers
semanticscholar   +1 more source

Factor VII Deficiency

2018
This chapter outlines the pathophysiology, clinical presentation, inheritance, and incidence of factor VII deficiency. The chapter describes the interaction with pregnancy and discusses the medical and anesthetic management of pregnant women with factor VII deficiency, including treatment of acute hemorrhage.
Joanne Douglas, James P. R. Brown
openaire   +2 more sources

LIVER TRANSPLANTATION FOR FACTOR VII DEFICIENCY

Transplantation, 2001
Factor VII deficiency is a serious, potentially lethal disorder of blood coagulation caused by a defect in hepatic factor VII synthesis. We report two children, sisters, both with severe, recurrent hemorrhagic complications from factor VII deficiency, successfully treated with orthotopic liver transplantation.
David Levi   +4 more
openaire   +3 more sources

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