Results 321 to 330 of about 448,079 (362)

Inhibitor development in patients with congenital factor VII deficiency, a study on 50 Iranian patients

Blood Coagulation and Fibrinolysis, 2019
&NA; Congenital factor VII (FVII) deficiency is a rare bleeding disorder with an estimated prevalence of 1 per 500 000 in the general population. On-demand replacement therapy is the main therapeutic choice in patients with congenital FVII deficiency ...
Mahmood Shams, A. Dorgalaleh, Nader Safarian, A. Emami, F. Zaker, S. Tabibian, M. Managhchi, Mohammad Faranoush, Tahereh Tabatabaei, Sedighe Satari, M. Rezvani   +10 more
semanticscholar   +1 more source

Congenital Combined Factor VII and Factor VIII Deficiency [PDF]

Acta Haematologica, 1980
This paper describes two family members who have a combined hereditary deficiency of factors VII and VIII. The propositus, a 16-year-old male, presented with recurrent gastrointestinal bleeding. He and his mother had moderate defects of factors VII and VIII. The propositus received factor VIII cover, during and after a laparatomy.
B R Miller, S J Machin
openaire   +2 more sources

Factor VII deficiency and its treatment in delivery with recombinant factor VII

European Journal of Obstetrics & Gynecology and Reproductive Biology, 2004
The authors present two cases of pregnant women with coagulation disorders--one with inherited deficiency of factor VII and the second with chronic hepatitis. Both cases were successfully treated with recombinant activated factor VII of coagulation (NovoSeven) in delivery. The advantages of using this product are discussed.
N. Milchev, B. Pehlivanov, G. Kroumov
openaire   +3 more sources

Active and Inactive Factor VII in Dubin‐Johnson Syndrome with Factor‐VII Deficiency, Hereditary Factor‐VII Deficiency and on Coumadin Administration

British Journal of Haematology, 1972
Summary. Factor VII was purified from a lyophilized powder of PTC complex (Hemoplex, Cutter Laboratories) and an antiserum was prepared in rabbits to the partially‐purified fraction. The antiserum was found to inhibit specifically factor VII of normal plasma and the activity of the purified factor‐VII preparation.Inactive factor‐VII‐like material was ...
Bracha Ramot, Mordechai Shani, M. Levanon, Eugenie Goldberg, Sarah Rimon   +4 more
openaire   +3 more sources

Combined Factor VII and Factor VIII Deficiency Due to a Casual Association of Heterozygosis for Factor VII Deficiency and Hemophilia A

Acta Haematologica, 1977
A patient with combined factor VII and factor VIII deficiency is discussed. The propositus is a 21-year-old male who presented a mild bleeding tendency. The patient appears to be a hemophilia and at the same time heterozygote for factor VII deficiency. This conclusion is based on the fact that heterozygosis for factor VII deficiency was present in the ...
Girolami A, Dal Bo Zanon R, FABRIS, FABRIZIO, Franzoso R.   +3 more
openaire   +4 more sources

Liver transplant for congenital factor VII deficiency

Pediatric Blood & Cancer, 2014
Congenital factor VII (FVII) deficiency is a rare, autosomal recessive bleeding disorder with a spectrum of phenotypes ranging from asymptomatic to life-threatening intra-cranial hemorrhage (ICH). Orthotopic liver transplantation has been described for definitive treatment in a few patients with severe manifestations.
Ruben E. Quiros Tejeira, Eric T. Rush, Melissa A. Acquazzino, Jill C. Beck   +3 more
openaire   +3 more sources

Carrier detection in factor VII congenital deficiency

British Journal of Haematology, 1985
SummaryThirty obligate and 28 possible carriers of factor VII congenital deficiency, belonging to 16 families, were studied in relation to the immunological variants to which the kindreds belonged, namely, VII+, VIIR and VII‐. Factor VII activity and antigen determinations in these subjects formed two phenotypical patterns: a discrepant pattern ...
N. Ciavarella, Guglielmo Mariani, Antonio Chistolini, P. M. Mannucci, M. G. Mazzucconi, G. D. Di Nucci, Jo Hermans, Franco Mandelli, A. Faiella, M. Berrettini, M. Orlando   +10 more
openaire   +4 more sources

Factor VII deficiency associated with valproate treatment

Pediatrics International, 2008
It has long been known that the anti-epileptic, valproate (VPA), which is used widely in the treatments of generalized and focal seizures, may cause subclinical alterations in both intrinsic and extrinsic coagulation pathways. These changes include thrombocyte dysfunction, thrombocytopenia, von Willebrand disease type I, deficiency of vitamin K ...
Kurul, Semra, Uenalp, Aycan, Dirik, Eray
openaire   +4 more sources

Combined Factor V and Factor VII Deficiency

Acta Haematologica, 1983
A patient suffering from cardiochalasia was found to be partially deficient in both coagulation factors V and VII. No bleeding tendency had been noticed. A family study showed that the father had factor VII deficiency with normal factor V, while the mother and 2 sisters had a reduced level of factor V and normal factor VII.
Federico Chiurazzi, Bruno Rotoli, Rossana D’Avino   +2 more
openaire   +2 more sources

Congenital Factor II Deficiency

2018
Coagulation factor (F) II (prothrombin) is a vitamin K-dependent coagulation factor which has an essential role in coagulation cascade. This protein is activated to thrombin by Factor X in the presence of FV and calcium. Congenital FII deficiency is an autosomal recessive bleeding disorder with an estimated incidence of 1:2,000,000 worldwide.
Rodney M. Camire, Shadi Tabibian, Akbar Dorgalaleh   +2 more
openaire   +2 more sources