Results 21 to 30 of about 15,991 (171)
Factor VII deficiency-related recurrent hemarthrosis in a female child – When to suspect?
Iraqi Journal of Hematology, 2021 Recurrent hemarthrosis is a common entity in children. Although recurrent hemarthrosis most often associated with hemophilia (VIII or IX deficiency), but rarely it can be associated with factor VII deficiency (FVIID).
Siyaram Didel +4 more
doaj +1 more source
Low-dose recombinant factor VIIa for massive bleeding
Swiss Medical Weekly, 2011 QUESTIONS UNDER STUDY: recombinant activated factor VII (rFVIIa) is used off-label for massive bleeding. There is no convincing evidence of the benefits of this practice and the minimal effective dose is unknown.
A Mordasini +6 more
doaj +1 more source
Thrombosis Journal, 2003 Background In spite of using heparin-coated extracorporeal circuits, cardiopulmonary bypass (CPB) is still associated with an extensive thrombin generation, which is only partially suppressed by the use of high dosages of heparin.
de Jong Dick S +3 more
doaj +1 more source
Journal of Medical Case Reports, 2023 Background The clotting or hemostasis system is a meticulously regulated set of enzymatic reactions that occur in the blood and culminate in formation of a fibrin clot.
Kenneth Newman +2 more
doaj +1 more source
Research and Practice in Thrombosis and Haemostasis, 2020 Hemostasis is a complex process involving the concerted action of molecular and vascular components. Its basic understanding as well as diagnostic and therapeutic aspects have greatly benefited from the use of monoclonal antibodies.
Ivan Peyron +8 more
doaj +1 more source
Adiponectin alleviate blood hypercoagulability via inhibiting endothelial cell apoptosis induced by oxidative stress in septic rats [PDF]
Iranian Journal of Basic Medical Sciences, 2018 Objective(s): The purpose of this study was to detect the protective effects of adiponectin on coagulation dysfunction and its mechanism in sepsis of rats.Materials and Methods: The experimental samples were composed of sham group, model group that was
Yun Hou +6 more
doaj +1 more source
Iraqi Journal of Hematology, 2022 BACKGROUND: Recombinant activated factor VII (FVII) is a product onetime evolved to stop bleeding occurring in hemophilia A and B patients with inhibitor, congenital FVII deficiency, Glanzmann disease, and in life-threatening bleeding.
Nidal Karim Al-Rahal +4 more
doaj +1 more source
Journal of Medical Case Reports, 2010 Introduction Vascular malformation is associated with coagulopathies, especially when hemostasis is challenged. Case presentation We present the case of an 11-year-old Hispanic girl with Klippel-Trenaunay-Weber syndrome that developed disseminated ...
Kecskes Susan +4 more
doaj +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Advanced Functional Materials, EarlyView.There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato +9 more
wiley +1 more source