Results 1 to 10 of about 65,543 (113)

International collaborative study for the calibration of a proposed World Health Organization International Standard for thromboplastin, human, recombinant: a report from the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC)—Scientific and Standardization Committee (SSC)/ISTH working group on prothrombin time/international normalized ratio standardization [PDF]

Research and Practice in Thrombosis and Haemostasis
Background: The availability of International Reference Preparations for thromboplastins, later on referred to as International Standards (ISs) for thromboplastins is essential for calibration of prothrombin time (PT) measurement systems and for the ...
Michelle P. van der Helm, Claudia J.J. van Rijn, Shanti S. Baktawar, Charmane F. Abdoel, Steve Kitchen, Michelle Bryant, Paula Brown, Armando Tripodi, Erica Scalambrino, Marigrazia Clerici, Petra Herbel, Anja Jünschke, Piet Meijer, Anne Stavelin, Craig Thelwell, Christa M. Cobbaert, Antonius M.H.P. van den Besselaar   +16 more
doaj   +2 more sources

A reproducible rat model for warfarin studies: Prothrombin time assessment with minimal blood using the CoaguChek XS and determination of an effective warfarin dosage [PDF]

Veterinární Medicína
Warfarin research in rats is often challenged by methodological inconsistencies and large blood volume requirements. This study aimed to validate a refined, reproducible rat model for serial prothrombin time (PT) monitoring using the CoaguChek XS, in ...
ET Akyol, MT Hekim, M Erol
doaj   +2 more sources

Case Report: Acquired hemophilia A presenting with recurrent arthritis-like joint swelling and musculoskeletal hematomas—a focused literature review [PDF]

Frontiers in Medicine
BackgroundAcquired hemophilia A (AHA) usually causes cutaneous, soft-tissue, or muscle bleeding; joint-dominant presentations are uncommon and may be mistaken for septic or inflammatory arthritis.Case presentationA man in his late 60s with no personal or
Jing Zhang, Lina Zhang, Sheng-Guang Li, Ji Li, Yadan Zou, Ting Long, Ruohan Yu, Yanfeng Zhang   +7 more
doaj   +2 more sources

A Novel Thromboplastin-Based Rat Model of Ischemic Stroke

Brain Sciences, 2021
The thromboembolic ischemia model is one of the most applicable for studying ischemic stroke in humans. The aim of this study was to develop a novel thromboembolic stroke model, allowing, by affordable tools, to reproduce cerebral infarction in rats.
Irina V. Ostrova, Sergei N. Kalabushev, Ivan A. Ryzhkov, Zoya I. Tsokolaeva   +3 more
doaj   +1 more source

The role of hemostatic changes in the pathogenesis of diabetic retinopathy

Journal of Education, Health and Sport, 2022
Introduction: The paper presents the results of the hemostasis system of rats with experimental diabetic retinopathy. Material and methods: Experimental studies were performed on white Wistar rats, which were divided into 2 groups: 1st group – intact
Nataliya Preys, Ivan Savytskyi
doaj   +1 more source

Lupus Antibody Mimicking Reduced Plasmatic Coagulation in a Patient With Atrial Fibrillation and Ischemic Stroke

Frontiers in Neurology, 2020
Background: Lupus anticoagulant (LA) owns procoagulant properties in vivo and prolongs phospholipid-dependent clotting times in vitro. The prolonged in vitro clotting time can be misinterpreted as a bleeding disorder.
Aydin Huseynov, Aydin Huseynov, Verena Haselmann, Maximillian Kittel, Thomas Bertsch, Angelika Alonso, Michael Neumaier, Martin Borggrefe, Martin Borggrefe, Ursula Hoffmann, Ursula Hoffmann   +10 more
doaj   +1 more source

Comparative Study and Analysis of Clotting Profiles Between Covid-19 And Non-Covid-19 Patients In Barau Dikko Teaching Hospital, Kaduna

UMYU Journal of Microbiology Research, 2021
Coronavirus disease 2019 (COVID-19) is associated with coagulation abnormalities—disordered hemostasis and high thrombotic risk. The aim of the study was to compare and analyze the clotting profiles between COVID-19 and non-COVID-19 ...
Abdulfatai, K., Abdullahi, B., Jaafaru, I. A., Ezeh, J. N., Haruna, D. S., Achi, M. F.   +5 more
doaj   +1 more source

Association of Abnormal Coagulation Tests in Dengue Fever with Clinical Outcomes of The Patients

Pakistan Armed Forces Medical Journal, 2022
Objective: To assess the coagulation test abnormalities (prothrombin time, activated partial thromboplastin time and fibrin degradation products) in dengue fever patients and its impact on clinical outcomes of the patient.
Zareen Irshad, Nazish Jaffar, Talat Zehra, Faiza Zeeshan, Sunila Tashfeen, Asma Sheikh   +5 more
doaj   +1 more source

Tissue Factor-Expressing Tumor-Derived Extracellular Vesicles Activate Quiescent Endothelial Cells via Protease-Activated Receptor-1

Frontiers in Oncology, 2017
Tissue factor (TF)-expressing tumor-derived extracellular vesicles (EVs) can promote metastasis and pre-metastatic niche formation, but the mechanisms by which this occurs remain largely unknown. We hypothesized that generation of activated factor X (FXa)
Sara P. Y. Che, Jeannie Y. Park, Tracy Stokol   +2 more
doaj   +1 more source

A comparison of two techniques of cell block preparation

Journal of Pathology of Nepal, 2019
Background: Cell block technique is a method of preparing cytological material so that it can be processed, sectioned, stained, and viewed as a histology section.
Anita Kasichhwa, Shreya Shrivastav, Ayushi Agrawal   +2 more
doaj   +1 more source