Results 181 to 190 of about 13,061,190 (344)

Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian, Peter Auguste, Amy Grove, Anna Brown, Janette Parr, Mubarak Patel, Furqan Butt, Jeremiah Donoghue, Mehdi Yousefi, Jo Parsons   +9 more
wiley   +1 more source

Selected cell receptor genotypes differentially modulate the ABO blood group influence on Factor VIII levels in severe aortic stenosis

Barbara Lunghi, Annalisa Castagna, Alessio Branchini, Marcello Baroni, Giovanna Marchetti, Gianni Mazzoni, Cristina Legnani, Marianna Spizzo, Gabriele Mango, Simonetta Friso, Nicola Martinelli, Francesco Bernardi   +11 more
openalex   +2 more sources

Phase 3 study of recombinant factor VIII Fc fusion protein in severe hemophilia A.

Blood, 2014
J. Mahlangu, J. Powell, M. Ragni, P. Chowdary, N. Josephson, I. Pabinger, H. Hanabusa, N. Gupta, R. Kulkarni, P. Fogarty, D. Perry, A. Shapiro, K. Pasi, Shashikant Apte, I. Nestorov, Haiyan Jiang, Shuanglian Li, S. Neelakantan, L. Cristiano, Jaya Goyal, J. Sommer, J. Dumont, Nigel Dodd, Karen Nugent, G. Vigliani, A. Luk, Aoife Brennan, Glenn F Pierce   +27 more
semanticscholar   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Induction of factor VIII tolerance by hemophilia gene transfer to eradicate factor VIII inhibitors. [PDF]

Blood Adv
Young G.
europepmc   +1 more source

Phosphatidylethanolamine Induces High Affinity Binding Sites for Factor VIII on Membranes Containing Phosphatidyl-L-serine [PDF]

, 1995
Gary E. Gilbert, Andrew A. Arena
openalex   +1 more source

Factor VIII in the Setting of Acute Ischemic Stroke Among Patients With Suspected Hypercoagulable State

Clinical and applied thrombosis/hemostasis, 2014
Tiffany R. Chang, Tiffany R. Chang, K. Albright, A. Boehme, A. Dorsey, E. Sartor, R. Kruse-Jarres, C. Leissinger, S. Martin-Schild   +8 more
semanticscholar   +1 more source

Increased Blood Levels of NfL, GFAP, and Placental Growth Factor After Radiotherapy to the Brain

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this study, we analyzed biomarkers of neuronal, glial, and vascular injury in longitudinal paired samples of blood and cerebrospinal fluid after prophylactic cranial irradiation in patients with small cell lung cancer. Neurofilament light chain protein (NfL) and glial fibrillary acidic protein (GFAP) increased in serum and cerebrospinal ...
Erik Fernström, Thomas Björk‐Eriksson, Pontus Erickson, Jan Nyman, Henrik Zetterberg, Marie Kalm   +5 more
wiley   +1 more source

Emicizumab, the factor VIII mimetic bispecific monoclonal antibody: effects on thrombin generation and thromboelastometry. [PDF]

Res Pract Thromb Haemost
Tripodi A, Clerici M, Scalambrino E, Arcudi S, Gualtierotti R, Novembrino C, Peyvandi F.   +6 more
europepmc   +1 more source

Endogenous factor VIII synthesis from the intron 22–inverted F8 locus may modulate the immunogenicity of replacement therapy for hemophilia A

, 2013
Gouri Shankar Pandey, Chen Yanover, Lisa M. Miller-Jenkins, Susan H. Garfield, Shelley A. Cole, Joanne E. Curran, Eric K. Moses, Natalia Rydz, Vijaya L. Simhadri, Chava Kimchi‐Sarfaty, David Lillicrap, Kevin R. Viel, Teresa M. Przytycka, Glenn F. Pierce, Tom E. Howard, Zuben E. Sauna, Jeanne M. Lusher   +16 more
openalex   +2 more sources