Results 211 to 220 of about 115,636 (264)
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Scandinavian Journal of Haematology, 1980
Because of the need to relate haemophilic samples to the normal population, the unit of Factor VIII clotting activity (VIII:C) was first defined as the amount in 1 ml. of normal plasma. However, because of wide variation in the normal population, and poor stability of VIII:C in plasma, pooled normal plasma is unsuitable as a reference standard for ...
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Because of the need to relate haemophilic samples to the normal population, the unit of Factor VIII clotting activity (VIII:C) was first defined as the amount in 1 ml. of normal plasma. However, because of wide variation in the normal population, and poor stability of VIII:C in plasma, pooled normal plasma is unsuitable as a reference standard for ...
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SUPPRESSION OF FACTOR VIII ANTIBODY BY COMBINED FACTOR VIII AND CYCLOPHOSPHAMIDE
Acta Medica Scandinavica, 1974Abstract. Four patients with severe haemophilia A complicated by inhibitors of factor VIII (corresponding to 0.5, 0.7, 1.0 and 2.5 U/ml plasma) and a non‐haemophilic woman with an acquired inhibitor of factor VIII (corresponding to 160 U/ml plasma) have been treated with a large single dose of factor VIII concentrate (4 000–8 000 U factor VIII) and ...
I M, Nilsson, U, Hedner, L, Holmberg
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In Vivo Interactions of Autoantibodies to Factor VIII with the Factor VIII Complex
Thrombosis and Haemostasis, 1982SummaryTwo non-haemophilic elderly patients who had developed autoantibodies to factor VIII were studied over a period of 9 months to 5 years. Sequential measurements of antibody to factor VIII (anti-VIII: C), factor VIII coagulant activity (VIII: C), factor VIII coagulant antigen (VIII: CAg), factor VIII-related antigen (VIIIR: Ag), and factor VIII ...
J P, Allain +5 more
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JAMA: The Journal of the American Medical Association, 1986
To the Editor.— Rock et al 1 reported that in studies in 1982, the stated content of ampules of lyophilized antihemophilic factor (AHF, factor VIII) concentrates often exceeded the measured content, as assayed in the authors' laboratory. They stated that this discrepancy, with its implications of systematic undertreatment of classic hemophilia, has ...
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To the Editor.— Rock et al 1 reported that in studies in 1982, the stated content of ampules of lyophilized antihemophilic factor (AHF, factor VIII) concentrates often exceeded the measured content, as assayed in the authors' laboratory. They stated that this discrepancy, with its implications of systematic undertreatment of classic hemophilia, has ...
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JAMA: The Journal of the American Medical Association, 1985
To the Editor.— Dr Waddell and colleagues 1 described the use of porcine factor VIII concentrate in a patient with factor VIII inhibitor. They gave in detail the disadvantages and complications of this material and prothrombin complex concentrates.
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To the Editor.— Dr Waddell and colleagues 1 described the use of porcine factor VIII concentrate in a patient with factor VIII inhibitor. They gave in detail the disadvantages and complications of this material and prothrombin complex concentrates.
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Porcine factor VIII therapy in patients with factor VIII inhibitors
1995A review is presented of the use of porcine factor VIII (F.VIII) in patients with F.VIII inhibitors and acquired or congenital hemophilia. This review is drawn partly from the published literature and partly from an international survey of the use of porcine F.VIII in patients with congenital hemophilia conducted under the auspices of the ISTH F.VIII ...
C, Hay, J N, Lozier
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Characteristics of the Factor VIII Protein and Factor XIII in Various Factor VIII Concentrates
Scandinavian Journal of Haematology, 1980The in vitro properties of 5 factor VIII preparations (AHF‐Kabi, Hemofil Hyland, AHF‐Profilate Abbott, Kryobulin Immuno and Factorate High Purity Armour) and an ordinary cryoprecipitate were studied with reference to factor VIII clotting activity (VIII:C), factor VIII clotting antigen (VIILCAg), factor VIII related antigen (VIIIR:Ag) (EI, IRMA, CIE ...
I M, Nilsson +3 more
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Quantitative Evaluation of Factor VIII in Factor VIII Products.
Blood, 2004Abstract Several factor VIII products, recombinant and natural, have been used for hemophilia A treatment worldwide. Typically, two activity-based assays (factor Xase and aPTT) are used for the assessment of factor VIII concentration in these products.
Saulius Butenas +4 more
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The Absorption of Human Factor VIII Neutralizing Antibody by Factor VIII
British Journal of Haematology, 1974Summary. A new technique has been devised for measuring the amount of human factor VIII neutralizing antibody that is absorbed by factor VIII. The method has been applied to factor VIII from normal donors and to factor VIII‐like antigen from haemophilic persons.
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Porcine Factor VIII in Factor VIII Antibody-Positive Hemophiliacs
Journal of Interferon Research, 1994rected against the factor VIII protein, and completely or partially neutralizing the plasma coagulant activity of the clotting factor, is associated with a variety of diseases, and these antibodies are often the cause of the life-threatening bleeds. Such inhibitors, designated as acquired hemophilia, are uncommon (found in 0.2-1.0 previously normal ...
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