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Factor VIII (Anti-hemophilic factor)
Journal of Chronic Diseases, 1970Abstract Factor VIII is a compound of high molecular weight which interacts with activated factor IX, calcium, and phospholipid to generate thromboplastin (activated factor X) for blood coagulation. It has the electrophoretic mobility of an α-2 globulin, and probably consists of both glycoprotein and phospholipid.
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Porcine Factor VIII in Factor VIII Antibody-Positive Hemophiliacs
Journal of Interferon Research, 1994rected against the factor VIII protein, and completely or partially neutralizing the plasma coagulant activity of the clotting factor, is associated with a variety of diseases, and these antibodies are often the cause of the life-threatening bleeds. Such inhibitors, designated as acquired hemophilia, are uncommon (found in 0.2-1.0 previously normal ...
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Factor VIII replacement is still the standard of care in haemophilia A.
Blood transfusion = Trasfusione del sangue, 2019L. Aledort +3 more
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