Factor VIII moiety of recombinant Factor VIII Fc fusion protein impacts Fc effector function and CD16+ NK cell activation. [PDF]
Lagassé HAD, Ou J, Sauna ZE, Golding B.
europepmc +1 more source
This study explores the use of fluorinated copolymers with varying fluorophilic side chain lengths to enhance PFAS affinity. The integration of electrochemical techniques demonstrates enhanced adsorbent regeneration, with molecular dynamics simulations providing insight into the molecular‐level interactions involved.
Anaira Román Santiago+7 more
wiley +1 more source
The Janus membrane integrates a superhydrophilic CNF@CTAB‐MXene layer with a superhydrophobic PTFE layer, enabling efficient solar‐driven water evaporation and electricity generation. It achieves an evaporation rate of 1.51 kg m−2 h−1 with excellent salt resistance and long‐term stability.
Yinan Li+7 more
wiley +1 more source
Efanesoctocog alfa: the renaissance of Factor VIII replacement therapy.
Dargaud Y+3 more
europepmc +1 more source
Atomistic Mechanism of Lipid Membrane Binding for Blood Coagulation Factor VIII with Molecular Dynamics Simulations on a Microsecond Time Scale. [PDF]
Avery NG+3 more
europepmc +1 more source
Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer+10 more
wiley +1 more source
The in vitro cross-reactivity and blood coagulation potential of recombinant porcine factor VIII in Japanese patients with acquired hemophilia A. [PDF]
Takeyama M+8 more
europepmc +1 more source
Atomic Size Misfit for Electrocatalytic Small Molecule Activation
This review explores the application and mechanisms of atomic size misfit in catalysis for small molecule activation, focusing on how structural defects and electronic properties can effectively lower the energy barriers of chemical bonds in molecules like H2O, CO2, and N2.
Ping Hong+3 more
wiley +1 more source
Combination of bolus and continuous infusion of factor VIII in a patient with severe hemophilia A undergoing on-pump coronary artery bypass graft surgery. [PDF]
Vander Zwaag S, Brose S, Fassl J.
europepmc +1 more source