Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley +1 more source
The in vitro cross-reactivity and blood coagulation potential of recombinant porcine factor VIII in Japanese patients with acquired hemophilia A. [PDF]
Takeyama M+8 more
europepmc +1 more source
In this manuscript, the processability of X2CrNiMo17‐12‐2 powder coated with silicon carbide, silicon, and silicon nitride nanoparticles is investigated. The amount of nanoparticles varies from 0.25 to 1 vol%. By coating the powder feedstock material with nanoparticles, an enlargement of the process window and an increase in the build rate are achieved.
Nick Hantke+5 more
wiley +1 more source
Combination of bolus and continuous infusion of factor VIII in a patient with severe hemophilia A undergoing on-pump coronary artery bypass graft surgery. [PDF]
Vander Zwaag S, Brose S, Fassl J.
europepmc +1 more source
The fabrication and post‐treatment via solvent annealing of poly(3,4‐ethylenedioxythiophene) polystyrene sulfonate‐based electrodes using spray deposition in a roll‐to‐roll setup are presented. The decrease in sheet resistance and its correlation with nanostructure and molecular structure in the electrodes as a function of the processing parameters is ...
Marie Betker+10 more
wiley +1 more source
Ex vivo evaluation of the effect of plasma-derived factor VIII/von Willebrand factor in patients with severe hemophilia A on emicizumab prophylaxis. [PDF]
Raventós A+9 more
europepmc +1 more source
Anticorpo monoclonal anti-fator VIII Monoclonal antibody anti-factor VIII
Eurípides Ferreira
doaj +1 more source
This study examines the mechanical properties of triply periodic minimal surfaces (TPMS)‐based lattices, analyzing 36 architectures in elastic and plastic regimes. It evaluates the applicability of beam‐based scaling laws to TPMS lattices. Rigidity arises from the alignment of members with the load direction and solid regions preventing rotation.
Lucía Doyle+2 more
wiley +1 more source
Efanesoctocog alfa: the renaissance of Factor VIII replacement therapy.
Dargaud Y+3 more
europepmc +1 more source
A phase 1/2 safety and efficacy study of TAK-754 gene therapy: The challenge of achieving durable factor VIII expression in haemophilia A clinical trials. [PDF]
Chapin J+13 more
europepmc +1 more source