This study proposes a sustainable solution for rainwater‐driven energy harvesting by harnessing the intrinsic properties of lignin in wood. The first demonstration of an all‐wood tribonegative material for liquid–solid triboelectric nanogenerators is presented, eliminating the need for fluorine‐containing polymers and functional additives. Abstract The
Xuetong Shi+8 more
wiley +1 more source
Efanesoctocog Alfa versus Standard and Extended Half-Life Factor VIII Prophylaxis in Adolescent and Adult Patients with Haemophilia A without Inhibitors. [PDF]
Klamroth R+9 more
europepmc +1 more source
Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson+12 more
wiley +1 more source
A phase 1/2 safety and efficacy study of TAK-754 gene therapy: The challenge of achieving durable factor VIII expression in haemophilia A clinical trials. [PDF]
Chapin J+13 more
europepmc +1 more source
The side‐chain configuration in the bay region of C‐shaped ortho‐benzodipyrrole‐based non‐fullerene acceptors plays a crucial role in their self‐assembly, single‐crystal structures, and optoelectronic properties. The closely correlated molecular structure and performance underscore the importance of minimizing A–A self‐aggregation and enhancing D–A ...
Yung‐Jing Xue+18 more
wiley +1 more source
Left Ventricular Thrombus With Silent Myocardial Infarction in a Patient With Factor V Leiden Mutation and High Factor VIII Levels: A Case Report. [PDF]
Zahid AS, Shariff M, Huggett R.
europepmc +1 more source
Mathematical modeling identifies clotting factor combinations that modify thrombin generation in normal and factor VIII-, IX-, or XI-deficient blood. [PDF]
Stobb MT+5 more
europepmc +1 more source
Efficacy of regular prophylaxis with a plasma-derived von Willebrand factor/factor VIII concentrate with a 1:1 activity ratio in reducing heavy menstrual bleeding in girls/women with von Willebrand disease. [PDF]
Kiss C+5 more
europepmc +1 more source
Efficacy and safety of plasma-derived von Willebrand factor/factor VIII concentrate (wilate) prophylaxis in children and adolescents with von Willebrand disease - WIL-31 study post hoc analysis. [PDF]
Sidonio RF+4 more
europepmc +1 more source