Plasma‐derived factor X concentrate compassionate use for hereditary factor X deficiency: Long‐term safety and efficacy in a retrospective data‐collection study [PDF]
Research and Practice in Thrombosis and Haemostasis, 2021 Background Coagadex is a high‐purity plasma‐derived factor X concentrate (pdFX) developed to treat hereditary factor X deficiency (FXD). Objective Evaluate the efficacy and safety of pdFX administered to patients with hereditary FXD.
James N. Huang +4 more
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Circulating Inhibitor against Factor X: A Rare Cause of Hemorrhagic Diathesis [PDF]
Case Reports in Hematology, 2023 Acquired coagulopathies resulting from factor X deficiency are rare and typically associated with amyloidosis or plasma cell dyscrasia. Factor X plays a pivotal role in the coagulation cascade, converting prothrombin into thrombin and facilitating the ...
P. Rossignon +3 more
doaj +2 more sources
Anesthesia strategy for factor X deficiency coagulopathy: case report [PDF]
Brazilian Journal of Anesthesiology, 2022 Factor X deficiency ranks among the rarest coagulopathies and has a variable presentation spectrum. We intend to present a proposal for anesthesia protocol for individuals with the coagulopathy.
Carla Isabel Ferreira +5 more
doaj +2 more sources
Successful Treatment of Factor X Deficiency in a Patient with Lymphoplasmacytic Lymphoma with Bendamustine Plus Rituximab Regimen: A Case Report and Literature Review [PDF]
Journal of Blood Medicine, 2021 Tarinee Rungjirajittranon, Yingyong Chinthammitr, Chattree Hantaweepant Division of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandCorrespondence: Chattree HantaweepantClinical Lecturer of ...
Rungjirajittranon T +2 more
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Haematologica, 2010 Background Heparanase is an endo-β-D-glucuronidase dominantly involved in tumor metastasis and angiogenesis. Recently, we demonstrated that heparanase is involved in the regulation of the hemostatic system.
Yona Nadir +5 more
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Membrane-bound model of the ternary complex between factor VIIa/tissue factor and factor X [PDF]
Blood Advances: Formation of the extrinsic complex (EC) on cell surfaces is the event that triggers the coagulation cascade. Tissue factor (TF) and factor VIIa (FVIIa) form the EC together with FX on phosphatidylserine-containing membranes, leading to FX activation by
Melanie P. Muller +5 more
doaj +2 more sources
A new look at TFPI inhibition of factor X activation. [PDF]
PLoS Computational BiologyBlood coagulation is a vital physiological process involving a complex network of biochemical reactions, which converge to form a blood clot that repairs vascular injury.
Fabian Santiago +5 more
doaj +2 more sources
A case report of congenital factor X deficiency in an adult patient [PDF]
SAGE Open Medical Case Reports, 2022 Factor X deficiency is one of the rarest coagulation disorders representing 10% of all rare bleeding diseases with a frequency of 1:1,000,000. A 39-year-old male patient with no previous medical conditions was admitted to the hospital with a left carpal ...
Rehab Y AL-Ansari +3 more
doaj +2 more sources
Glioblastoma Cells Express and Secrete Alternatively Spliced Transcripts of Coagulation Factor X [PDF]
BiomedicinesBackground: Patients with cancer often develop a prothrombotic state that can evolve into venous and arterial thrombosis, which is associated with poor clinical outcomes.
Xiaotian Li +17 more
doaj +2 more sources
A Rare Cause of Acquired Factor X Deficiency in an 87-Year-Old Female [PDF]
Case Reports in Hematology, 2021 Factor X deficiency is a rare coagulopathy that can be inherited or acquired. Acquired factor X deficiency has been associated with plasma cell dyscrasias, amyloids, and use of vitamin K antagonists.
Ayrton Bangolo +6 more
doaj +2 more sources