Results 141 to 150 of about 19,832,698 (194)
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Seminars in Thrombosis and Hemostasis, 2009
Factor X (FX) deficiency is a rare, recessively inherited bleeding disorder representing 10% of all rare bleeding diseases and affecting 1 in every 1,000,000 people. Its clinical presentation places FX deficiency among the most severe of the rare coagulation defects, typically including hemarthroses, hematomas, and umbilical cord, gastrointestinal, and
Marzia Menegatti, Flora Peyvandi
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Factor X (FX) deficiency is a rare, recessively inherited bleeding disorder representing 10% of all rare bleeding diseases and affecting 1 in every 1,000,000 people. Its clinical presentation places FX deficiency among the most severe of the rare coagulation defects, typically including hemarthroses, hematomas, and umbilical cord, gastrointestinal, and
Marzia Menegatti, Flora Peyvandi
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The Factor‐X Defect: Recognition of Abnormal Forms of Factor X
British Journal of Haematology, 1970Summary. Six patients with the ‘Factor‐X defect’ have been investigated. At least five different forms of the defect were recognized by the use of the following laboratory tests: the kaolin cephalin clotting time as a measure of intrinsic clotting, the factor‐X assay employing either brain extract or Russell's viper venom, and the neutralization of a ...
A. Lurie +3 more
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Abnormal Factor X (Factor X Friuli) Coagulation Disorder
Acta Haematologica, 1973A new case with the abnormal factor X (factor X Friuli) coagulation disorder is presented: a 32-year- old female who was born outside Friuli and who complained of a bleeding tendency since childhood.
A. Girolami +3 more
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One Missense Mutation in the Factor X Gene Causing Factor X Deficiency—Factor X Kanazawa
International Journal of Hematology, 2001We investigated the molecular basis of factor X deficiency in a Japanese patient whose factor X activity and antigen level were 45% and 50% of normal control values, respectively. All exons and intron/exon junctions of the factor X gene were studied using a strategy combining polymerase chain reaction (PCR) amplification and nonradioactive single ...
Tomoe Mizutani +8 more
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Factor X Vorarlberg, A New Variant of Hereditary Factor X Deficiency [PDF]
The proposita, a 56 years old woman, has a mild bleeding tendency. Prothrombin time was 112 sec (control 17.0 sec), stypven time 13.7 sec (control 11.5 sec) and APTT 54 sec (control 40 sec). Factor I, II (funct.and imm.), V, VII, VIII, IX, XI, XII, AT III were normal. - Factor X activity was < 1% by extrinsic system assay (tissue thromboplastin), 12%
G. Mähr +3 more
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A NEW VARIANT OF FACTOR X DEFICIENCY (FACTOR X ROMA). [PDF]
A 13 years-old-girl was admitted in our Hospital for a large muscle hematoma of left psoas. At age 3 she had a severe tonsillar bleeding following angina. Afterwards she suffered from easy bruisability and recurrent epistaxis. Prothrombin time (PT) was slightly prolonged (14.7 sec, control 12 sec, INR 1.5), while a more marked prolongation in aPTT was ...
V. De Stefano +3 more
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Assessment of Factor VII and Factor X
Thrombosis and Haemostasis, 1966SummaryA method is described to separate factor VII from factor X in normal serum using electrophoresis in a polyvinyl chloride block. A potent source of factor X is obtained. This may be used in correction studies and for assessment of deficiencies of factor VII in patients.
Pegrum Gd +3 more
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Blood Reviews, 1994
Factor X circulates as a serine protease which is converted to the active form at the point of convergence of the intrinsic and extrinsic coagulation pathways. Subsequently, the enzymatic species, factor Xa, is involved in macromolecular complex formation with its cofactor factor Va, a phospholipid surface and calcium to convert prothrombin into ...
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Factor X circulates as a serine protease which is converted to the active form at the point of convergence of the intrinsic and extrinsic coagulation pathways. Subsequently, the enzymatic species, factor Xa, is involved in macromolecular complex formation with its cofactor factor Va, a phospholipid surface and calcium to convert prothrombin into ...
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Thrombosis and Haemostasis, 1971
SummaryA monospecific antiserum against factor X was prepared in rabbits. The antiserum precipitated factor X in human plasma and serum and monkey serum. The antiserum was used to :1. demonstrate the presence of factor X precursor in blood from patients under anticoagulant therapy,2.
Gladhaug A, Prydz H
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SummaryA monospecific antiserum against factor X was prepared in rabbits. The antiserum precipitated factor X in human plasma and serum and monkey serum. The antiserum was used to :1. demonstrate the presence of factor X precursor in blood from patients under anticoagulant therapy,2.
Gladhaug A, Prydz H
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Measurements in a forest reveal a previously unknown atmospheric oxidant that acts as a source of sulphuric acid — one of the main precursors for the formation and growth of aerosol particles and clouds.
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