Results 171 to 180 of about 9,057,173 (269)

SensRORing cholesterol to drive protumoral myelopoiesis

open access: yesMolecular Oncology, EarlyView.
Bleve et al. uncover a cholesterol‐driven immune evasion pathway, where RORγ‐dependent myelopoiesis shapes tumor immunosuppression. Targeting RORγ and PCSK9 emerges as a strategy to boost cancer immunotherapy. Protumoral myelopoiesis is a determinant of immunoevasion and tumor spread in many malignancies.
Sara Gennari, Luigi Nezi, Teresa Manzo
wiley   +1 more source

NMR-identification of the interaction between BRCA1 and the intrinsically disordered monomer of the Myc-associated factor X. [PDF]

open access: yesProtein Sci
Epasto LM   +7 more
europepmc   +1 more source

[Congenital factor X deficiency: a retrospective analysis of 11 cases]. [PDF]

open access: yesZhonghua Xue Ye Xue Za Zhi, 2022
Li RW   +7 more
europepmc   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Hereditary factor X deficiency in America survey: impact on quality of life and burden of disease in patients and caregivers. [PDF]

open access: yesBlood Coagul Fibrinolysis
Branchford B   +5 more
europepmc   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

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