Results 21 to 30 of about 19,325,472 (304)
Therapeutic Advances in Hematology, 2018 Hemophilia A, characterized by impaired or absent expression of factor VIII, has long been managed via direct factor replacement. Functionally, factor VIII acts as a cofactor for factor IXa and allows activation of factor X, which, in combination with ...
Tristan E. Knight, M. Callaghan
semanticscholar +1 more source
Journal of Thrombosis and Haemostasis, 2018 Essentials Plasma‐derived factor X concentrate (pdFX) is used to treat hereditary factor X deficiency. pdFX pharmacokinetics, safety and efficacy were assessed in factor X‐deficient women/girls.
R. Kulkarni +3 more
semanticscholar +1 more source
Haematologica, 2008 Due to a homozygous Gly204Arg mutation in the factor X (FX) gene no detectable FX antigen was found in the plasma of a one-year old patient with severe bleeding diathesis.
Zsuzsanna Bereczky +7 more
doaj +1 more source
Smooth integers and the Dickman $ρ$ function [PDF]
J. Anal. Math. 151 (2023), no. 1, 139-169, 2022 We establish an asymptotic formula for $\Psi(x,y)$ whose shape is $x \rho(\log x/\log y)$ times correction factors. These factors take into account the contributions of zeta zeros and prime powers and the formula can be regarded as an (approximate) explicit formula for $\Psi(x,y)$. With this formula at hand we prove oscillation results for $\Psi(x,y)$,
arxiv +1 more source
Lipid specificity of the membrane binding domain of coagulation factor X
Journal of Thrombosis and Haemostasis, 2017 Essentials Membrane‐binding GLA domains of coagulation factors are essential for proper clot formation. Factor X (FX) is specific to phosphatidylserine (PS) lipids through unknown atomic‐level interactions.
Melanie P. Muller +3 more
semanticscholar +1 more source
Factor X deficiency: a comment on two recent case studies
The Journal of Haemophilia Practice, 2023 Hereditary factor X deficiency (HFXD) is a rare genetic bleeding disorder, affecting approximately 1 in 1,000,000 individuals globally, and resulting in abnormally low activity of clotting factor X (FX). Diagnosis may occur early in life, particularly in
Branchford Brian
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The role of algebraic solutions in planar polynomial differential systems [PDF]
Math. Proc. Cambridge Philos. Soc. 143 (2007), no. 2, 487--508, 2005 We study a planar polynomial differential system, given by \dot{x}=P(x,y), \dot{y}=Q(x,y). We consider a function I(x,y)=\exp \{h_2(x) A_1(x,y) \diagup A_0(x,y) \} h_1(x) \prod_{i=1}^{\ell} (y-g_i(x))^{\alpha_i}, where g_i(x) are algebraic functions, A_1(x,y)=\prod_{k=1}^r (y-a_k(x)), A_0(x,y)=\prod_{j=1}^s (y-\tilde{g}_j(x)) with a_k(x) and \tilde{g ...
arxiv +1 more source
Haemophilia, 2016 Hereditary factor X (FX) deficiency is a rare bleeding disorder affecting 1:500 000 to 1:1 000 000 of individuals. Until recently, no specific replacement factor concentrate was available.
Steve Austin +4 more
semanticscholar +1 more source
Haemophilia, 2016 Maintaining haemostasis in surgery is challenging for hereditary rare bleeding disorders in which multi‐coagulation‐factor concentrates are the only therapeutic option. Hereditary factor X (FX) deficiency affects 1:500 000 to 1:1 000 000 individuals, and
M. Escobar +5 more
semanticscholar +1 more source
Helicobacter pylori Infection Maybe a Risk Factor for Cardiac Syndrome X
Frontiers in Cardiovascular Medicine, 2022 PurposeCardiac syndrome X (CSX) is a condition with normal coronary angiography but angina pectoris. Chronic inflammation caused by Helicobacter pylori (H. pylori) infection may play a pathogenic role in CSX.
Dong-Hong Zhang +8 more
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