Results 41 to 50 of about 8,980,980 (348)

Helicobacter pylori Infection Maybe a Risk Factor for Cardiac Syndrome X

open access: yesFrontiers in Cardiovascular Medicine, 2022
PurposeCardiac syndrome X (CSX) is a condition with normal coronary angiography but angina pectoris. Chronic inflammation caused by Helicobacter pylori (H. pylori) infection may play a pathogenic role in CSX.
Dong-Hong Zhang   +8 more
doaj   +1 more source

On the Factorization of lacunary polynomials [PDF]

open access: yesarXiv, 2022
This paper addresses the factorization of polynomials of the form $F(x) = f_{0}(x) + f_{1}(x) x^{n} + \cdots + f_{r-1}(x) x^{(r-1)n} + f_{r}(x) x^{rn}$ where $r$ is a fixed positive integer and the $f_{j}(x)$ are fixed polynomials in $\mathbb Z[x]$ for $0 \le j \le r$.
arxiv  

Antifactors of regular bipartite graphs

open access: yes, 2020
Let $G=(X,Y;E)$ be a bipartite graph, where $X$ and $Y$ are color classes and $E$ is the set of edges of $G$. Lov\'asz and Plummer \cite{LoPl86} asked whether one can decide in polynomial time that a given bipartite graph $G=(X,Y; E)$ admits a 1-anti ...
Lu, Hongliang, Wang, Wei, Yan, Juan
core   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Complement’s C1 Complex, Factor H and the X Factor: A Personal Tribute to Prof. Robert B. Sim

open access: yesViruses, 2021
It is with great sadness that I am writing this obituary for my mentor, colleague and friend, Bob, i [...]
Uday Kishore
doaj   +1 more source

Dynatomic polynomials, necklace operators, and universal relations for dynamical units [PDF]

open access: yesNew York J. Math. 28 (2022) 534-556, 2021
Given a generic polynomial $f(x)$, the generalized dynatomic polynomial $\Phi_{f,c,d}(x)$ vanishes at precisely those $\alpha$ such that $f^c(\alpha)$ has period exactly $d$ under iteration of $f(x)$. We show that the shifted dynatomic polynomials $\Phi_{f,c,d}(x) - 1$ often have generalized dynatomic factors, and that these factors are in ...
arxiv  

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Neonatal presentation of factor X deficiency

open access: yesIndian Journal of Health Sciences and Biomedical Research KLEU
Factor X is a Vitamin K-dependent serine protease synthesized in the liver. It is a key factor of the coagulation cascade as it is the first enzyme of a common pathway that leads to the formation of a stable fibrin clot.
Arjani Patra   +3 more
doaj   +1 more source

Heparanase enhances the generation of activated factor X in the presence of tissue factor and activated factor VII

open access: yesHaematologica, 2010
Background Heparanase is an endo-β-D-glucuronidase dominantly involved in tumor metastasis and angiogenesis. Recently, we demonstrated that heparanase is involved in the regulation of the hemostatic system.
Yona Nadir   +5 more
doaj   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

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