Results 41 to 50 of about 2,704,633 (236)

Structural and Functional Investigation of activated form of blood coagulation factor X

پژوهان, 2014
Introduction: Coagulation factor X is an important protein in the blood coagulation pathway. It contains significant structural features that affect its function.
Giti Kalantarian, Roya Avazpoor Tarkalki, Roghayeh Abasali Poor Kabireh, Nasrin Sheikh, Zahra Karimi   +4 more
doaj  

The global epidemiology of acquired factor X deficiency

Hematology
Objectives To summarize available data and contribute to a broader understanding of the global incidence and prevalence of acquired factor X deficiency.Methods A comprehensive review of English-language publications from PubMed and Embase was conducted ...
Kristy Iglay, Molly L. Aldridge, Mirella Calcinai, Eric Wolford, Aneel A. Ashrani   +4 more
doaj   +1 more source

X - FACTOR EVALUATION UNDER RPI-X REGULATION FOR INDIAN ELECTRICITY DISTRIBUTION UTILITIES [PDF]

Journal of Engineering Science and Technology, 2017
With regulators’ growing interest in improving operational efficiency and quality supply, the time is nearing when performance based regulation will become norm for regulating the distribution tariff in Indian electricity distribution sector.
PAVAN KHETRAPAL, TRIPTA THAKUR, ALOK GUPTA   +2 more
doaj  

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

ImageNet-X: Understanding Model Mistakes with Factor of Variation Annotations [PDF]

, 2022
Badr Youbi Idrissi, Diane Bouchacourt, Randall Balestriero, Ivan Evtimov, Caner Hazırbaş, Nicolas Ballas, P. Vincent, Michal Drozdzal, David López-Paz, Mark Ibrahim   +9 more
openalex   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Combined Factor VII and X Deficiency

Online Journal of Health & Allied Sciences, 2011
Factor VII deficiency and factor X deficiency and very rare disorders individually. Combined Factor VII and X is a rare congenital blood disorder with very few cases reported in the literature.
Gursharan Singh Narang,, Sunita Arora,, Jivtesh Singh Pahwa,   +2 more
doaj  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source