Results 41 to 50 of about 26,876,546 (349)

Beyond the X Factor: Relevance of Sex Hormones in NAFLD Pathophysiology

open access: yesCells, 2021
Non-alcoholic fatty liver disease (NAFLD) is a major health issue worldwide, being frequently associated with obesity, unbalanced dietary regimens, and reduced physical activity. Despite their greater adiposity and reduced physical activity, women show a
Sara Della Torre
doaj   +1 more source

Heterozygosity for nuclear factor one x affects hippocampal-dependent behaviour in mice. [PDF]

open access: yesPLoS ONE, 2013
Identification of the genes that regulate the development and subsequent functioning of the hippocampus is pivotal to understanding the role of this cortical structure in learning and memory.
Lachlan Harris   +10 more
doaj   +1 more source

Dynamics of Dimensions in Factor Space Cosmology [PDF]

open access: yes, 1995
We consider multidimensional cosmological models with a generalized space-time manifold M = R x M_1 ...x M_n, composed from a finite number of factor spaces M_i, i=1,..n.
Bleyer   +13 more
core   +4 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

Neonatal presentation of factor X deficiency

open access: yesIndian Journal of Health Sciences and Biomedical Research KLEU
Factor X is a Vitamin K-dependent serine protease synthesized in the liver. It is a key factor of the coagulation cascade as it is the first enzyme of a common pathway that leads to the formation of a stable fibrin clot.
Arjani Patra   +3 more
doaj   +1 more source

Inherited Moderate Factor X Deficiency Presenting as Cardiac Tamponade

open access: yesCase Reports in Hematology, 2019
Factor X deficiency is a rare bleeding disorder that varies in the severity of its clinical manifestations. The symptoms of this disorder can occur at any age, although most severe cases appear in childhood.
Tamer Othman   +4 more
doaj   +1 more source

Helicobacter pylori Infection Maybe a Risk Factor for Cardiac Syndrome X

open access: yesFrontiers in Cardiovascular Medicine, 2022
PurposeCardiac syndrome X (CSX) is a condition with normal coronary angiography but angina pectoris. Chronic inflammation caused by Helicobacter pylori (H. pylori) infection may play a pathogenic role in CSX.
Dong-Hong Zhang   +8 more
doaj   +1 more source

NGC 2992 in an X-ray high state observed by XMM: Response of the Relativistic Fe K$\alpha$ Line to the Continuum [PDF]

open access: yes, 2009
We present the analysis of an XMM observation of the Seyfert galaxy NGC 2992. The source was found in its highest level of X-ray activity yet detected, a factor $\sim 23.5$ higher in 2--10 keV flux than the historical minimum.
Arnaud   +26 more
core   +2 more sources

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

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