A Case of Haemorrhages caused by Multiple Myeloma Induced Factor Deficiencies: A Bleeding Enigma [PDF]
A 74-year-old male patient presented with anaemia, thrombocytopenia, and extensive haemorrhages over both thighs and back. A coagulation work-up revealed markedly elevated Prothrombin Time (PT) and activated Partial Thromboplastin Time (aPTT).
Abhijith Lakshman+3 more
doaj +1 more source
Haemophilia A and B are X-linked inherited bleeding disorders, resulting in the deficiency of clotting factor VIII and IX, respectively. Since the introduction of recombinant clotting factor concentrates in the early 1990s, the major safety concern for ...
Buckner Tyler W.+5 more
doaj +1 more source
Search for cold and hot gas in the ram pressure stripped Virgo dwarf galaxy IC3418
We present IRAM 30m sensitive upper limits on CO emission in the ram pressure stripped dwarf Virgo galaxy IC3418 and in a few positions covering HII regions in its prominent 17 kpc UV/Ha gas-stripped tail.
Combes, F.+5 more
core +2 more sources
Real Polynomial Gram Matrices Without Real Spectral Factors [PDF]
It is well known that a non-negative definite polynomial matrix (a polynomial Gramian) $G(t)$ can be written as a product of its polynomial spectral factors, $G(t) = X(t)^H X(t)$. In this paper, we give a new algebraic characterization of spectral factors when $G(t)$ is real-valued. The key idea is to construct a representation set that is in bijection
arxiv
Hereditary Factor X (Stuart-Prower Factor) Deficiency [PDF]
Inherited deficiency of Factor X was first reported way back in mid 1950s by workers who were studying patients with a haemorrhagic disease resembling factor VII deficiency. It is also known by the surnames of the patients who were first found to manifest the defect (Stuart and Prower).
Pramod K. Gupta, Harsh Kumar, S Kumar
openaire +2 more sources
MMP-3 deficiency alleviates endotoxin-induced acute inflammation in the posterior eye segment [PDF]
Matrix metalloproteinase-3 (MMP-3) is known to mediate neuroinflammatory processes by activating microglia, disrupting blood-central nervous system barriers and supporting neutrophil influx into the brain. In addition, the posterior part of the eye, more
Becker+26 more
core +2 more sources
An Alternative Proof of the $H$-Factor Theorem [PDF]
Let $H: V(G) \rightarrow 2^{\mathbb{N}}$ be a set mapping for a graph $G$. Given a spanning subgraph $F$ of $G$, $F$ is called a {\it general factor} or an $H$-{\it factor} of $G$ if $d_{F}(x)\in H(x)$ for every vertex $x\in V(G)$. $H$-factor problems are, in general, $NP$-complete problems and imply many well-known factor problems (e.g., perfect ...
arxiv
Concerning Order and Disorder in the Ensemble of Cu-O Chain Fragments in Oxygen Deficient Planes of Y-Ba-Cu-O [PDF]
In connection with numerous X-ray and neutron investigations of some high temperature superconductors (YBa$_2$Cu$_3$O$_{6+x}$ and related compounds) a non-trivial part of the structure factor, coming from partly disordered Cu-O-$\dots$-O-Cu chain fragments, situated within basal planes, CuO$_x$, can be a subject of theoretical interest.
arxiv +1 more source
Bruton's Tyrosine Kinase Is Required for Activation of Iκb Kinase and Nuclear Factor κb in Response to B Cell Receptor Engagement [PDF]
Mutations in the gene encoding Bruton's tyrosine kinase (btk) cause the B cell deficiency diseases X-linked agammaglobulinemia (XLA) in humans and X-linked immunodeficiency (xid) in mice.
Anderson+48 more
core +2 more sources
Cochlear implantation in hemophilia B—a rare case report
Background Hemophilia B is an X-linked inherited disease, mainly caused by deficiency of factor IX. Severity of the disease is manifested by the factor IX deficiency in the blood.
Chetan Yadav+3 more
doaj +1 more source