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Danazol therapy in factor X deficiency
Haemophilia, 2001Factor X (FX) deficiency is a rare coagulation disorder that usually presents with bleeding manifestations and is treated with fresh frozen plasma or prothrombin complex concentrates. We report a case of FX deficiency in which the patient presented with bleeding as well as thrombosis.
S, Mukhopadhyay +3 more
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Hämostaseologie, 2019
Factor X (FX) deficiency (FXD) is an extremely rare autosomal recessive hereditary hematologic disorder, affecting approximately one in 1,000,000 of the general population.
O. Grottke +5 more
semanticscholar +1 more source
Factor X (FX) deficiency (FXD) is an extremely rare autosomal recessive hereditary hematologic disorder, affecting approximately one in 1,000,000 of the general population.
O. Grottke +5 more
semanticscholar +1 more source
Journal of the American Veterinary Medical Association, 1997
Severe congenital deficiency of factor X was diagnosed in a 3-year-old castrated male domestic shorthair cat with clinical signs of generalized seizures and prolonged bleeding after venipuncture. Heritability of factor X deficiency was suspected because of a prolonged Russell's viper venom time in the dam and reductions in factor X activity in the dam ...
J L, Gookin +4 more
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Severe congenital deficiency of factor X was diagnosed in a 3-year-old castrated male domestic shorthair cat with clinical signs of generalized seizures and prolonged bleeding after venipuncture. Heritability of factor X deficiency was suspected because of a prolonged Russell's viper venom time in the dam and reductions in factor X activity in the dam ...
J L, Gookin +4 more
openaire +2 more sources
JAMA, 1974
Isolated factor X deficiency in association with abnormal plasma antithrombin activity was recognized in a 59-year-old man with amyloidosis and signs and symptoms of calf pain suggestive of thrombophlebitis. Venographic studies excluded venous thrombosis, and, despite major coagulation abnormalities, there was no hemorrhagic tendency.
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Isolated factor X deficiency in association with abnormal plasma antithrombin activity was recognized in a 59-year-old man with amyloidosis and signs and symptoms of calf pain suggestive of thrombophlebitis. Venographic studies excluded venous thrombosis, and, despite major coagulation abnormalities, there was no hemorrhagic tendency.
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Acquired Factor X Deficiency and Amyloidosis
American Journal of Clinical Pathology, 1977A selective acquired Factor X deficiency is an unusual occurrence. Six cases of an acquired Factor X deficiency in association with amyloidosis have been reported. This paper describes two additional cases, suggesting that this relationship may be more than coincidental.
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Treatment of Amyloidosis Associated Factor X Deficiency
Thrombosis and Haemostasis, 1976SummaryThis is the tenth patient in thirteen years to be reported with the findings of an isolated factor X deficiency associated with primary amyloidosis. A favorable response to factor IX concentrate was manifested by temporary clinical and laboratory correction of her diathesis.
J A, Spero +3 more
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Factor X Deficiency and Systemic Amyloidosis
New England Journal of Medicine, 1977The association of an isolated acquired factor X (Stuart-factor) deficiency and systemic acquired amyloidosis has been sporadically reported over the last 15 years,1 , 2 and over two thirds of the ...
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Systemic Amyloidosis Associated With Factor X Deficiency
Acta Pathologica Japonica, 1984An autopsy case of amyloidosis associated with factor X deficiency is reported. The patient showed a markedly decreased level of factor X (9% normal) and an extremely shortened half‐life of intravenously infused factor X. Amyloid deposition was present in most of the visceral organs with special involvement of the liver and spleen.
H, Shibuya +4 more
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Factor X and its deficiency states
Haemophilia, 1997Summary. Factor X is one of the vitamin‐K‐dependent serine proteases. As a result of its position at the convergence of the intrinsic and extrinsic pathways of the clotting cascade, it plays a crucial role in blood coagulation. Factor X interacts with components of both pathways of coagulation, leading to its activation and the formation of the ...
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One Missense Mutation in the Factor X Gene Causing Factor X Deficiency—Factor X Kanazawa
International Journal of Hematology, 2001We investigated the molecular basis of factor X deficiency in a Japanese patient whose factor X activity and antigen level were 45% and 50% of normal control values, respectively. All exons and intron/exon junctions of the factor X gene were studied using a strategy combining polymerase chain reaction (PCR) amplification and nonradioactive single ...
E, Morishita +8 more
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