Results 1 to 10 of about 141 (118)

Therapeutic Plasma Exchange After Spontaneous Intracranial Hemorrhage for a Patient With Antiphospholipid Syndrome and Lupus Anticoagulant Hypoprothrombinemia. [PDF]

J Clin Apher
ABSTRACT Antiphospholipid syndrome (APS) is characterized by the presence of antiphospholipid antibodies (aPL), macro‐ and micro‐vascular thromboembolic complications. Lupus anticoagulant‐hypoprothrombinemia (LAHPS) may confound the diagnosis and management of bleeding. Catastrophic APS has a category 1 indication for therapeutic plasma exchange (TPE).
Nicholas J, Wali J, Ellis-Caleo T, Virk MS, Yunce M.   +4 more
europepmc   +2 more sources

Acquired Hypoprothrombinemia [PDF]

Blood, 1957
Abstract Hypoprothrombinemia was encountered in 105 patients including cases of vitamin K deficiency, liver disease, newborns, Dicumarol-type drug therapy and a few miscellaneous disorders. The findings stress the association of acquired hypoprothrombinemia with deficiencies proconvertin and PTC and suggest that these three proteins are ...
J H, FERGUSON, J W, FRESH, J H, LEWIS, E, SPAUGH, M B, ZUCKER   +4 more
openaire   +2 more sources

Hypoprothrombinemia: case report [PDF]

Blood, 1978
A patient with a significant history of spontaneous and posttraumatic bleeding was found to have hypoprothrombinemia. His prothrombin (factor II) activity by clotting assay was 9.5% and his factor II antigen was 5%. Crossed immunoelectrophoresis and sucrose density gradient ultracentrifugation of the patient's plasma showed his prothrombin to be ...
R R, Montgomery, A, Otsuka, W E, Hathaway   +2 more
openaire   +3 more sources

Patient with lupus anticoagulant caused aPTT prolongation corrected with prednisolone treatment and later anticoagulation treatment due to chronic atrial fibrillation

Clinical Case Reports, Volume 11, Issue 6, June 2023., 2023
Key Clinical Message Lupus anticoagulant caused aPTT prolongation in rare case can cause bleeding tendency especially when combined with other hemostasis abnormalities. In such cases, aPTT value can be corrected by immunosuppressants within several days of treatment.
Marlena Frydrysiak, Paulina Pachniak, Anna Krysicka, Dariusz Moczulski   +3 more
wiley   +1 more source

Lupus anticoagulant hypoprothrombinemia syndrome: A case report

Clinical Case Reports, Volume 11, Issue 4, April 2023., 2023
Abstract Lupus anticoagulant hypoprothrombinemia syndrome (LAHPS) is a rare entity associated with an increased risk of hemorrhage. Corticosteroids have been used in its treatment with favorable results. We present the case of a 54‐year‐old female patient with a personal history of Lupus diagnosed with LAHPS following an episode of cerebellar ...
Natalia Acedo, Alejandro Alonso, Eliana Samantha Feijoó, Cristina García, Ana M. Ortiz, Adrián Alegre   +5 more
wiley   +1 more source

Neuropsychiatric Lupus and Lupus Nephritis Successfully Treated with Combined IVIG and Rituximab: An Alternative to Standard of Care

Case Reports in Rheumatology, Volume 2022, Issue 1, 2022., 2022
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with unpredictable course and flares. The clinical manifestation can vary from mild to severe and life‐threatening disease. Infection is the primary cause of mortality in hospitalized SLE patients.
Mohamed M. Cheikh, Abdullah K. Bahakim, Moayad K. Aljabri, Saad M. Alharthi, Sanad M. Alharthi, Abdullah K. Alsaeedi, Saad F. Alqahtani, Constantine Saadeh   +7 more
wiley   +1 more source

A case of congenital prothrombin deficiency with two concurrent mutations in the prothrombin gene

Research and Practice in Thrombosis and Haemostasis, Volume 5, Issue 4, May 2021., 2021
Abstract Congenital prothrombin deficiency is an extremely rare, autosomal recessive bleeding disorder with a prevalence of 1 in 2 million individuals. Here, we report a case of congenital prothrombin deficiency with two concurrent mutations in the prothrombin gene (F2), affecting the heavy B chain.
Eman M. Mansory, Pratibha Bhai, Alan Stuart, Lori Laudenbach, Bekim Sadikovic, Alejandro Lazo‐Langner   +5 more
wiley   +1 more source

Monitoring of anticoagulation in thrombotic antiphospholipid syndrome

Journal of Thrombosis and Haemostasis, Volume 19, Issue 4, Page 892-908, April 2021., 2021
Abstract Anticoagulation is central to the management of thrombotic antiphospholipid syndrome (APS). The standard anticoagulant treatment for thrombotic APS is life‐long warfarin or an alternative vitamin K antagonist. The role of direct oral anticoagulants for thrombotic APS is not established due to the lack of definitive evidence and has recently ...
Hannah Cohen, Maria Efthymiou, Katrien M. J. Devreese   +2 more
wiley   +1 more source

Lupus anticoagulant hypoprothrombinemia syndrome associated with a hemorrhagic ovarian cyst in a girl with systemic lupus erythematosus : a case report [PDF]

Childhood Kidney Diseases
Lupus anticoagulant hypoprothrombinemia syndrome (LAHPS) is a rare entity characterized by the presence of lupus anticoagulant (LA) and prothrombin (factor II) deficiency. It may cause severe bleeding contrary to classical antiphospholipid syndrome. Here,
Min Hwa Son, Hyung Eun Yim
doaj   +1 more source

Lupus anticoagulant-hypoprothrombinemia syndrome with lupus nephritis in a girl misdiagnosed with immunoglobulin A nephropathy: a case report [PDF]

Childhood Kidney Diseases
Distinguishing lupus nephritis (LN) from other glomerulopathies, such as immunoglobulin A nephropathy (IgAN), poses a diagnostic challenge owing to overlapping clinical and histopathologic findings. Lupus anticoagulant-hypoprothrombinemia syndrome (LAHPS)
Chung Ho Lee, Yo Han Ahn, Hee Gyung Kang, Ji Hyun Kim   +3 more
doaj   +1 more source