Results 11 to 20 of about 143 (118)

Therapeutic Plasma Exchange After Spontaneous Intracranial Hemorrhage for a Patient With Antiphospholipid Syndrome and Lupus Anticoagulant Hypoprothrombinemia. [PDF]

J Clin Apher
ABSTRACT Antiphospholipid syndrome (APS) is characterized by the presence of antiphospholipid antibodies (aPL), macro‐ and micro‐vascular thromboembolic complications. Lupus anticoagulant‐hypoprothrombinemia (LAHPS) may confound the diagnosis and management of bleeding. Catastrophic APS has a category 1 indication for therapeutic plasma exchange (TPE).
Nicholas J, Wali J, Ellis-Caleo T, Virk MS, Yunce M.   +4 more
europepmc   +2 more sources

Patient with lupus anticoagulant caused aPTT prolongation corrected with prednisolone treatment and later anticoagulation treatment due to chronic atrial fibrillation

Clinical Case Reports, Volume 11, Issue 6, June 2023., 2023
Key Clinical Message Lupus anticoagulant caused aPTT prolongation in rare case can cause bleeding tendency especially when combined with other hemostasis abnormalities. In such cases, aPTT value can be corrected by immunosuppressants within several days of treatment.
Marlena Frydrysiak, Paulina Pachniak, Anna Krysicka, Dariusz Moczulski   +3 more
wiley   +1 more source

Lupus anticoagulant hypoprothrombinemia syndrome: A case report

Clinical Case Reports, Volume 11, Issue 4, April 2023., 2023
Abstract Lupus anticoagulant hypoprothrombinemia syndrome (LAHPS) is a rare entity associated with an increased risk of hemorrhage. Corticosteroids have been used in its treatment with favorable results. We present the case of a 54‐year‐old female patient with a personal history of Lupus diagnosed with LAHPS following an episode of cerebellar ...
Natalia Acedo, Alejandro Alonso, Eliana Samantha Feijoó, Cristina García, Ana M. Ortiz, Adrián Alegre   +5 more
wiley   +1 more source

Neuropsychiatric Lupus and Lupus Nephritis Successfully Treated with Combined IVIG and Rituximab: An Alternative to Standard of Care

Case Reports in Rheumatology, Volume 2022, Issue 1, 2022., 2022
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with unpredictable course and flares. The clinical manifestation can vary from mild to severe and life‐threatening disease. Infection is the primary cause of mortality in hospitalized SLE patients.
Mohamed M. Cheikh, Abdullah K. Bahakim, Moayad K. Aljabri, Saad M. Alharthi, Sanad M. Alharthi, Abdullah K. Alsaeedi, Saad F. Alqahtani, Constantine Saadeh   +7 more
wiley   +1 more source

A case of congenital prothrombin deficiency with two concurrent mutations in the prothrombin gene

Research and Practice in Thrombosis and Haemostasis, Volume 5, Issue 4, May 2021., 2021
Abstract Congenital prothrombin deficiency is an extremely rare, autosomal recessive bleeding disorder with a prevalence of 1 in 2 million individuals. Here, we report a case of congenital prothrombin deficiency with two concurrent mutations in the prothrombin gene (F2), affecting the heavy B chain.
Eman M. Mansory, Pratibha Bhai, Alan Stuart, Lori Laudenbach, Bekim Sadikovic, Alejandro Lazo‐Langner   +5 more
wiley   +1 more source

Monitoring of anticoagulation in thrombotic antiphospholipid syndrome

Journal of Thrombosis and Haemostasis, Volume 19, Issue 4, Page 892-908, April 2021., 2021
Abstract Anticoagulation is central to the management of thrombotic antiphospholipid syndrome (APS). The standard anticoagulant treatment for thrombotic APS is life‐long warfarin or an alternative vitamin K antagonist. The role of direct oral anticoagulants for thrombotic APS is not established due to the lack of definitive evidence and has recently ...
Hannah Cohen, Maria Efthymiou, Katrien M. J. Devreese   +2 more
wiley   +1 more source

Pathophysiology of coronavirus disease 2019 for wound care professionals

International Wound Journal, Volume 17, Issue 6, Page 1935-1940, December 2020., 2020
Abstract There is pressing urgency to understand the pathogenesis of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) which causes Coronavirus disease 2019 (COVID‐19). The tissue tropism of SARS‐CoV‐2 includes not only the lung but also the vascular and integumentary systems.
Sammy Al‐Benna
wiley   +1 more source

Acquired Factor XI Deficiency with Lupus Anticoagulant in a Pregnant Woman Diagnosed by the Eruptions and Pain in Fingers

Case Reports in Obstetrics and Gynecology, Volume 2020, Issue 1, 2020., 2020
We report a case of acquired factor XI deficiency with lupus anticoagulant (LA) in a 28‐year‐old primigravida who presented with finger pain and eruptions on her palms and fingers during the 3rd trimester of pregnancy. The patient complained of pain and reddening of the fingers at 30 weeks of gestation.
Rie Nakajima, Atsuko Togo, Yasuhira Kanno, Masaru Hayashi, Kanako Mitsuzuka, Hitoshi Ishimoto, Akihide Ohkuchi   +6 more
wiley   +1 more source

Using Preoperative Therapeutic Plasma Exchange in Lupus Anticoagulant Hypoprothrombinemia Syndrome to Achieve Hemostatic Factor II Activity: A Case Report

Journal of Clinical Apheresis, Volume 41, Issue 4, August 2026.
ABSTRACT Lupus anticoagulant hypoprothrombinemia syndrome (LA‐HPS) is a rare cause of acquired factor II deficiency associated with lupus anticoagulant due to antiprothrombin antibody, which predisposes to bleeding rather than thrombosis. We report a case of a 48‐year‐old female with LA‐HPS resulting in a bleeding diathesis due to acquired prothrombin ...
Puja Panwar, Sean G. Yates, Rebecca Yarborough, Yu‐Min Shen   +3 more
wiley   +1 more source

Engineering Gossypol‐Free Cottonseeds for Future Global Food Security and Agricultural Sustainability

Food Frontiers, Volume 7, Issue 1, January 2026.
This study depicting the role of transcriptomics, RNA interference (RNAi), and CRISPR/Cas9 technologies in the breeding of glandless cottonseed and glanded cotton tissues. This approach demonstrates the potential of cotton as a dual‐purpose crop, serving both the fiber industry and as a sustainable food and feed source.
Teame Gereziher Mehari, Muhammad Yousaf Shani, Junfeng Tang, Hui Fang, Muhammad Jawad Umer, Fang Liu, Kai Wang, Dengbing Yao, Muhammad K. R. Khan, Baohua Wang   +9 more
wiley   +1 more source