Discovery and development of Factor Xa inhibitors (2015-2022). [PDF]
As a pathological coagulation process, thrombus can lead to many serious diseases, including ischemic stroke, acute myocardial infarction (AMI), acute coronary syndrome (ACS), and deep venous thrombosis (DVT).
Zheng W, Dai X, Xu B, Tian W, Shi J.
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Expedited surgery does not increase transfusion rates for patients with geriatric hip fracture taking factor Xa inhibitors. [PDF]
. Objectives:. Geriatric patients who sustain hip fractures and are taking factor Xa inhibitors (Xa-I) experience surgical delay. Our institution developed a pharmacokinetic protocol to formally guide and expedite surgical timing for these patients.
Wang J +6 more
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Predictors of hematoma expansion in intracerebral hemorrhage associated with factor Xa inhibitors. [PDF]
BackgroundImproving the outcomes of patients with intracerebral hemorrhage (ICH) associated with factor Xa inhibitors remains a clinical challenge. Andexanet alfa, a specific reversal agent for factor Xa inhibitors, has the potential to mitigate hematoma
Komatsu Y +6 more
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Factor Xa inhibitors in hemodialysis: OK-for now! [PDF]
Banchs JE.
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Urine-based point-of-care testing for factor-Xa-inhibitors in acute ischemic stroke patients: a feasibility study. [PDF]
Doeppner TR +7 more
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The 5 most frequently asked questions about factor Xa inhibitors. [PDF]
Wang TF, Carrier M.
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Oral direct thrombin inhibitors or oral factor Xa inhibitors versus conventional anticoagulants for the treatment of pulmonary embolism. [PDF]
Li M +11 more
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The impact of body composition variability on coagulation monitoring in patients on direct oral factor Xa inhibitors for treatment of venous thromboembolism. [PDF]
Kurzmann-Guetl K +9 more
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Incomplete harms reporting in systematic reviews of direct oral factor Xa inhibitors. [PDF]
Rea J +9 more
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Position statement of the Polish Society of Gastroenterology on the use of andexanet alfa in patients with gastrointestinal bleeding taking factor Xa inhibitors. [PDF]
Adrych K +4 more
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