Results 221 to 230 of about 788,607 (367)

Endovascular Stenting and Factor Xa Inhibitors for Filter-Associated Chronic IVC Occlusion: A Case Series. [PDF]

Am J Case Rep
Cao P, Luo X, Gao R, Li Y, Li L, Zhang Y, Liu X.   +6 more
europepmc   +1 more source

Construction and In Vitro Testing of a Novel Fab-Hirudin–Based Fusion Protein That Targets Fibrin and Inhibits Thrombin in a Factor Xa–Dependent Manner

, 2003
Karlheinz Peter, Amitabh Gupta, Thomas K. Nordt, Simone Bauer, Marschall S. Runge, Christoph Bode   +5 more
openalex   +1 more source

Sulfated, low-molecular-weight lignins are potent inhibitors of plasmin, in addition to thrombin and factor Xa: Novel opportunity for controlling complex pathologies [PDF]

, 2009
Brian L. Henry, May H. Abdel Aziz, Qibing Zhou, Umesh R. Desai   +3 more
openalex   +1 more source

Population Pharmacokinetic/Pharmacodynamic and Exposure–Response Modeling of Garadacimab in Healthy Volunteers and Patients With Hereditary Angioedema

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 5, Page 954-963, May 2025.
ABSTRACT Hereditary angioedema (HAE) is a rare genetic disease that manifests as recurrent, unpredictable, and potentially life‐threatening attacks of angioedema. Garadacimab is a first‐in‐class, fully human, monoclonal antibody targeting activated factor XII (FXIIa) that is under clinical development for the long‐term prophylaxis of HAE attacks.
Ramon Garcia, Shen Cheng, Fiona Glassman, Ankur Sharma, Bernardo De Miguel‐Lillo, Matthew Wiens, Curtis Johnston, John‐Philip Lawo, Ingo Pragst, Jonathan French, Dan Polhamus, Partha Nandy   +11 more
wiley   +1 more source

Adverse Events of Factor Xa Inhibitors in Pediatric Patients: A Meta-analysis and Pharmacovigilance Study. [PDF]

Paediatr Drugs
Chong S, Sun L, Mu G, Hua M, Xiang Q, Cui Y.   +5 more
europepmc   +1 more source

Factor Xa inhibitors versus vitamin K antagonist in morbidly obese patients with venous thromboembolism: a systematic review and meta-analysis. [PDF]

BMC Cardiovasc Disord, 2023
Park DY, An S, Arif AW, Sana MK, Vij A.
europepmc   +1 more source

Lactate orchestrates metabolic hemodynamic adaptations through a unique combination of venocontraction, artery relaxation, and positive inotropy

Acta Physiologica, Volume 241, Issue 5, May 2025.
Abstract Aim H+ facilitates metabolic blood flow regulation while negatively impacting cardiac contractility. Cardiovascular consequences of conjugate bases accumulating alongside H+ remain unclear. Here, we evaluate the cardiovascular effects of nine prominent carboxylates—particularly lactate, 3‐hydroxybutyrate, and butyrate—linked to metabolic and ...
Casper Homilius, Jacob M. Seefeldt, Jakob Hansen, Roni Nielsen, Frank V. de Paoli, Ebbe Boedtkjer   +5 more
wiley   +1 more source

Effect of the frequently used antiepileptic drugs carbamazepine, gabapentin, and pregabalin on the pharmacokinetics of edoxaban and other oral factor xa inhibitors in healthy volunteers. [PDF]

Front Pharmacol
Lenard A, Hermann SA, Stoll F, Burhenne J, Foerster KI, Czock D, Mikus G, Meid AD, Haefeli WE, Blank A.   +9 more
europepmc   +1 more source

An Evaluation of Time to Therapeutic Range of Intravenous Unfractionated Heparin After Transitioning From Direct Oral Factor Xa Inhibitors. [PDF]

Hosp Pharm, 2023
Lawing L, Yook J, Ray M, Smith SE.
europepmc   +1 more source

Characteristics of the hemostatic action of KFA-1411, an inhibitor of coagulation factor Xa (FXa), in humans and various animals.

, 2003
Kiyoto Hara, Toshiki Honma, Akane Matsuzawa, Atsushi Matsuzawa, Masahiko Uchida, Takashi Koizumi, Satoshi Akahane, Masami Kojima   +7 more
openalex   +2 more sources