Results 201 to 210 of about 23,492 (249)

The management of factor XI deficiency

Haemophilia, 1998
Summary. Factor XI deficiency leads to a more variable bleeding tendency than haemophilia A or B. Although severely deficient individuals are likely to bleed excessively especially after surgery in areas of the body with increased fibrinolysis, there is evidence that some partially deficient individuals are at risk of excessive bleeding.
C. A. Lee, C. M. Kessler, D. Varon, U. Martinowitz, M. Heim, P. H. B. BOLTON‐MAGGS   +5 more
openaire   +2 more sources

Factor XI Deficiency

JAMA: The Journal of the American Medical Association, 1977
To the Editor.— The article by Jokl and Federico entitled "Myositis Ossificans Traumatica: Association with Hemophilia (Factor XI Deficiency) in a Football Player" (237:2215-2216, 1977) is not adequately documented as a case of factor XI deficiency. Factor XI assays in their patient were determined to be 46% and 52%.
openaire   +2 more sources

Prostatectomy in Factor XI Deficiency

Journal of Urology, 1977
Factor XI deficiency, an uncommon inherited coagulopathy characterized by an absence of bleeding history but bleeding after an operation or trauma, has not been reported previously in urologic patients. The diagnosis is made by a specific factor assay after an abnormal partial thromboplastin time and the treatment is fresh frozen plasma.
openaire   +2 more sources

Factor X Deficiency

2018
This chapter outlines the pathophysiology, clinical presentation, inheritance, and incidence of factor XI deficiency. The chapter describes the interaction with pregnancy and discusses the medical and anesthetic management of pregnant women with factor XI deficiency, including treatment of acute hemorrhage.
James P. R. Brown, Joanne Douglas
openaire   +1 more source

Inhibitors to Factor XI in Patients With Severe Factor XI Deficiency

Seminars in Hematology, 2006
Factor XI (FXI) deficiency is a rare bleeding disorder that may arise from any of a number of missense, nonsense, splice site, insertion, and deletion mutations within the FXI gene. Severely affected patients are at considerable risk of developing inhibitors to FXI and, although spontaneous bleeding is uncommon in such patients, bleeding after surgery ...
Ophira, Salomon, Ariella, Zivelin, Tami, Livnat, Uri, Seligsohn   +3 more
openaire   +2 more sources

Congenital Factor XI Deficiency: An Update

Seminars in Thrombosis and Hemostasis, 2013
Severe factor XI (FXI) deficiency is an injury-related bleeding disorder, common in Ashkenazi Jews (with two mutations prevailing), but rare worldwide (with heterogeneous mutations). In the past two decades, more than 220 mutations in the FXI gene have been reported in patients with FXI deficiency, of which 7 showed a founder effect.
Stefano, Duga, Ophira, Salomon
openaire   +2 more sources

The Management of Factor XI Deficiency in Pregnancy

Seminars in Thrombosis and Hemostasis, 2016
Management of factor XI (FXI) deficiency in pregnancy is complicated by lack of correlation between FXI level and bleeding risk. Clinicians should be vigilant about the potential for prolonged or excessive bleeding following miscarriage or termination of pregnancy, or postpartum hemorrhage (PPH).
Joanna, Davies, Rezan, Kadir
openaire   +2 more sources

A Sardinian Family with Factor XI Deficiency

Hämostaseologie, 2019
Introduction Factor XI (FXI) deficiency is a bleeding disorder which causes a bleeding tendency after trauma or surgery. An inhibitor may be acquired secondary to replacement therapy. Aim To study on genetical and functional grounds a family admitted to our Haemostasis and Thrombosis Centre for an incidental finding of a ...
Barcellona, Doris, Favuzzi, Giovanni, Vannini, Maria Luigia, Piras, Sebastiana Maria, Ruberto, Maria Filomena, Grandone, Elvira, Marongiu, Francesco   +6 more
openaire   +4 more sources

Factor XI Deficiency and a Platelet Defect

Haemostasis, 2009
A patient with a lifelong bleeding tendency of moderate severity was found to have both factor XI deficiency and a long bleeding time. There was a significant deficiency of platelet factor 3, but other parameters of platelet function were normal.
M, Winter, J, Needham, P, Barkhan
openaire   +2 more sources

Inheritance and bleeding in factor XI deficiency

British Journal of Haematology, 1988
A study of 20 Jewish and four non‐Jewish kindreds transmitting factor XI deficiency (164 individuals) confirmed inheritance to be autosomal with severe deficiency in homozygotes (mean factor XI level 3.8 u/dl, SD 2.91) and partial deficiency in heterozygotes (mean factor XI level 57 u/dl, SD 10.42; normal mean factor XI level 96 u/dl, SD 11.6).
P H, Bolton-Maggs, B, Young Wan-Yin, A H, McCraw, J, Slack, P B, Kernoff   +4 more
openaire   +2 more sources