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Feline Factor XII (Hageman) Deficiency
American Journal of Veterinary Research, 1977SUMMARY A coagulation profile from a clinically normal female cat revealed an intrinsic coagulation defect characterized by prolonged activated partial thromboplastin time, with normal bleeding time, platelet count, and prothrombin time. Subsequent correction studies, utilizing activated partial thromboplastin time, confirmed factor XII deficiency ...
R A, Green, F, White
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Clinical implications of factor XII deficiency
Oral Surgery, Oral Medicine, Oral Pathology, 1989A patient with known factor XII deficiency underwent extraction of four impacted third molars. Significant preoperative laboratory values included a partial thromboplastin time (PTT) of greater than 100 seconds and a factor XII level of less than 1%. The third molars were removed without any significant intraoperative or postoperative bleeding.
R J, McDonough, C L, Nelson
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Rosai–Dorfman disease with factor XII deficiency
Clinical Rheumatology, 2009A 17-year-old female patient presented with chronic symmetrical oligoarthritis of both knees and ankles, xerostomia, xerophthalmia, multiple bilateral lymphadenopathies in the cervical region, and bilateral parotid enlargement with the histological finding of chronic sialoadenitis.
Gunal, Esen Kasapoglu +9 more
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Factor XII Deficiency and Thrombosis
Thrombosis and Haemostasis, 1979The clinical implication of Factor XII deficiency has been much discussed. Most authors agree that these patients are generally asymptomatic; others have found a bleeding tendency; and some 15 scattered cases with occlusive vascular disease have heen collected from world’ literature. Since 1972 we have studied 8 patients with this deficiency associated
J. Pizzuto +4 more
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New Families with Factor XII Deficiency
Thrombosis and Haemostasis, 1970SummaryHereditary factor XII deficiency is reported in 2 unrelated Norwegian families.Case 1 was a 50 year old female, who was investigated because of a subcutaneous hematoma of unexplained cause. She had bruised easily, but neither she nor members of her family had suffered from definite and marked bleeding tendency.
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Hageman Factor (Factor XII) Deficiency in Marine Mammals
Science, 1969Hematologic and coagulation studies were conducted on Atlantic bottlenose dolphins and killer whales. Hematologic values were similar to those in man. These animals differed from other mammals in that the Hageman factor (factor XII) was absent and this absence caused marked prolongation of coagulation.
A J, Robinson +2 more
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Molecular analysis of factor XII gene in Thai patients with factor XII deficiency
Blood Coagulation & Fibrinolysis, 2013Factor XII is the initiating protein of the intrinsic coagulation pathway. It activates factor X after being activated by the so called 'contact system'. Both congenital factor XII deficiency, usually without bleeding symptoms, and several factor XII polymorphisms with possible thrombotic tendency have been described.
Pon, Singhamatr +2 more
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Effect of Factor XII Deficiency on Pregnancy and Parturition
Thrombosis and Haemostasis, 1979SummaryThe clotting parameter of a primigravida with factor XII deficiency was studied during her third trimester of pregnancy, labor and post-partum; and compared with those of her newborn male infant. Sharp increases in factors VII, VIII, IX, X and moderate increases in factors II and XI were documented during pregnancy and at labor.
P, Saidi, M, Siegelman, V B, Mitchel
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Bilten za hematologiju i transfuziju, 1985
The work presents classical form and variant of F XII deficiency. Although a rare disorder, F XII deficiency can lead to bleeding, particularly after injuries and surgeries. Further laboratory investigation of patients with pathological APTT is required.
C, Vera +4 more
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The work presents classical form and variant of F XII deficiency. Although a rare disorder, F XII deficiency can lead to bleeding, particularly after injuries and surgeries. Further laboratory investigation of patients with pathological APTT is required.
C, Vera +4 more
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A New Family with Congenital Factor XII Deficiency
Acta Haematologica, 1975The case of a patient with Hageman trait and his family study are reported. Commercial plasma thromboplastin time (PTT) reagents showed a good sensitivity for detecting the plasma defect. By prolonging the incubation time of the mixture containing PTT reagent and factor XII-deficient plasma the abnormal coagulation times were not corrected.
T, Barbui, E, Dini
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