Results 61 to 70 of about 1,777 (237)

Holomorphic Factorization of Matrices of Polynomials [PDF]

open access: yes, 1999
This paper considers some work done by the author and Catlin [CD1,CD2,CD3] concerning positivity conditions for bihomogeneous polynomials and metrics on bundles over certain complex manifolds. It presents a simpler proof of a special case of the main result in [CD3], providing also a self-contained proof of a generalization of the main result from [CD1]
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Chemical Systems with Limit Cycles. [PDF]

open access: yesBull Math Biol, 2023
Erban R, Kang HW.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Factorization of operators on $C^*$-algebras

open access: yes, 1997
Let $A$ be a $C^*$-algebra. It is shown that every absolutely summing operator from $A$ into $\ell_2$ factors through a Hilbert space operator that belongs to the 4-Schatten- von Neumann class.
Randrianantoanina, Narcisse
core   +1 more source

Bidiagonal factoring of Stirling matrices

open access: yesMaple Transactions
Stirling cycle numbers and Stirling partition numbers have many combinatorial applications. A symmetric matrix built from Stirling cycle numbers, which is known to be totally nonnegative, appears as https://oeis.org/A137854 in the Online Encyclopedia of Integer Sequences. In this paper we give analytical bidiagonal factorings of these matrices.
Robert M. Corless   +2 more
openaire   +1 more source

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