Results 101 to 110 of about 257 (215)

Optimal model‐based design of experiments for parameter precision: Supercritical extraction case

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract This study investigates the process of chamomile oil extraction from flowers. A parameter‐distributed model consisting of a set of partial differential equations is used to describe the governing mass transfer phenomena in a cylindrical packed bed with solid chamomile particles under supercritical conditions using carbon dioxide as a solvent ...
Oliwer Sliczniuk, Pekka Oinas
wiley   +1 more source

A‐optimal model‐based design of experiments for processes with uncertain inputs

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Model‐based design of experiments (MBDoE) techniques are tools for selecting experimental conditions that enable accurate parameter estimation for mechanistic models. Most MBDoE approaches assume that the selected experimental conditions will be implemented perfectly, without uncertainties in the independent variables.
Bright Ofori, Iman Moshiritabrizi, Anh‐Duong Vo, Kimberley B. McAuley   +3 more
wiley   +1 more source

An analytical review of statistical methods and designs in agricultural science Una revisión analítica de diseños y métodos estadísticos en ciencias agrícolas

Agronomía Colombiana, 1994
Scientilic papers of six wellknown international journal of agricultural research (Agronomy Journal, Crop Science, Plant Physiology, Phytopathology, Plant Disease, Journal of Economic Entomology) and the Revista ICA of Colombia, were revised taking the ...
Martínez W. Orlando, Galindo Ricardo
doaj  

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

Cancer Nexus, EarlyView.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang   +5 more
wiley   +1 more source

Optimization of UPLC method for simultaneous determination of rosuvastatin and rosuvastatin degradation products

Acta Chimica Slovenica, 2017
An ultra-performance liquid chromatographic method for simultaneous determination of rosuvastatin and rosuvastatin degradation products was developed and optimized by using fractional factorial experimental design.
Jure Zakrajšek, Katarina Bevc-Černilec, Simona Bohanec, Uroš Urleb   +3 more
doaj   +2 more sources

Major Adverse Cardiac Events with Ondansetron: A Systematic Review

Clinical Pharmacology &Therapeutics, EarlyView.
Evidence base: 170 randomized trials, 23,421 adults, predominantly single‐dose IV ondansetron, mean follow‐up 20 days. Observed outcomes: Major adverse cardiac events were rare, no ventricular arrhythmias or torsades de pointes observed. Conclusion: Ondansetron was not associated with increased mortality or serious cardiac arrhythmias in adult ...
Michael Cristian Garcia, Bhavya Gandhi, Faisal Quadri, Mahnoor Shahab, Kassie Rong, Genevieve Ramnarine, Ishleen Sudan, Sophia Zhang, Michelle Yu, Sara Mojdehi, Lawrence Mbuagbaw, Anne M. Holbrook   +11 more
wiley   +1 more source

Assessing Overall Survival Benefits in Advanced Cancers: The Role of External Comparator Cohort Studies with Real‐World Data

Clinical Pharmacology &Therapeutics, EarlyView.
External comparator cohort (ECC) studies with real‐world data (RWD) may provide more reliable estimates of treatment differences compared to single‐arm trials (SAT), yet they face limitations such as selection bias and data heterogeneity. This study assessed the perceived strength of evidence of ECC studies compared to SAT and randomized controlled ...
Francesco Pignatti, Tarec Christoffer El‐Galaly, Martin Kaiser, Kimmo Porkka, Robin Doeswijk, Peter Mol, Donna R. Rivera, Catherine C. Lerro, Ulrich‐Peter Rohr, Patrice Verpillat, Antonios Valachis, Dario Trapani, Massimo Di Maio, Nicola Latino, Raul Cordoba, Nathan Cherny, Miriam Koopman, Diogo Martins‐Branco, George Pentheroudakis, Douwe Postmus   +19 more
wiley   +1 more source

When Corporations Nudge for Good: Examining the Effectiveness of Corporate Social Marketing Initiatives in Influencing Intention to Change

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Firms invest heavily in corporate social initiatives (CSIs), yet evidence of behaviour change remains limited. This study examines whether corporate social marketing (CSM) elicits stronger behavioural intentions to change than other CSI formats, such as philanthropy and cause‐related marketing (CRM), and identifies the psychological mechanisms
Paul Blaise Issock Issock
wiley   +1 more source

Purification of Li2CO3 Obtained through Pyrometallurgical Treatment of NMC Black Mass from Electric Vehicle Batteries

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
Lithium carbonate (Li2CO3) obtained from the black mass of recycled lithium batteries is dissolved in water under controlled conditions to remove lithium fluoride (LiF), which is present at a concentration of 3.08 % by weight. The dissolution is carried out at temperatures below 10 °C, and it has been demonstrated that lower temperatures result in ...
Laura Rosso, Lorena Alcaraz, Olga Rodríguez‐Largo, Félix A. López   +3 more
wiley   +1 more source

Statistical optimization of the growth factors for Chaetoceros neogracile using fractional factorial design and central composite design.

Journal of microbiology and biotechnology, 2009
Statistical experimental designs; involving (i) a fractional factorial design (FFD) and (ii) a central composite design (CCD) were applied to optimize the culture medium constituents for production of a unique antifreeze protein by the Antartic microalgae Chaetoceros neogracile.
Sung-Eun, Jeong, Jae-Kweon, Park, Jeong-Dong, Kim, In-Jeong, Chang, Seong-Joo, Hong, Sung-Ho, Kang, Choul-Gyun, Lee   +6 more
openaire   +1 more source