Results 171 to 180 of about 15,863 (273)

Machine Learning for Predictive Modeling in Nanomedicine‐Based Cancer Drug Delivery

Med Research, EarlyView.
The integration of AI/ML into nanomedicine offers a transformative approach to therapeutic design and optimization. Unlike conventional empirical methods, AI/ML models (such as classification, regression, and neural networks) enable the analysis of complex clinical and formulation datasets to predict optimal nanoparticle characteristics and therapeutic
Rohan Chand Sahu, Sanchit Arora, Dinesh Kumar, Ashish Kumar Agrawal   +3 more
wiley   +1 more source

Assessment of volatile component stability in Guanxin Jieyu granules through gas chromatography in accordance with Q14 guidelines. [PDF]

Sci Rep
Chen L, Zhang T, Fang N, Wan H, He Y, Wan H.   +5 more
europepmc   +1 more source

Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease

Movement Disorders, EarlyView.
Abstract Background Huntington's disease (HD) is characterized by early, selective, progressive vulnerability of striatal medium spiny neurons (MSNs). Proenkephalin (PENK), a precursor of opioid peptides abundantly expressed in MSNs, is a promising biomarker of striatal integrity, but region‐specific associations and its potential for early‐stage ...
Mena Farag, Michael J. Murphy, Nicola Z. Hobbs, Michela Leocadi, Kate Fayer, Olivia Thackeray, Johan Gobom, Marc Ciosi, Amanda Heslegrave, Henrik Zetterberg, Douglas R. Langbehn, Darren G. Monckton, Edward J. Wild, Sarah J. Tabrizi, Rachael I. Scahill   +14 more
wiley   +1 more source

What influences individual preferences for responsiveness in oral health services? A discrete choice experiment in Türkiye. [PDF]

BMJ Open
Özbek M, Yardım MS.
europepmc   +1 more source

Analysis of a Modified Version of the Inventory of Non‐Ataxia Signs Over 12 Years in Patients with Friedreich's Ataxia in the EFACTS Study

Movement Disorders, EarlyView.
Abstract Background Friedreich's ataxia is a rare, neurodegenerative, multisystem disorder. While ataxia is a hallmark, non‐ataxia signs, including muscle weakness, spasticity, and dysphagia are equally disabling. The Inventory of Non‐Ataxia Signs (INAS) is a symptom list transformable to a 16‐item count.
Stella Andrea Lischewski, Imis Dogan, Paola Giunti, Michael H. Parkinson, Caterina Mariotti, Alexandra Durr, Claire Ewenczyk, Sylvia Boesch, Wolfgang Nachbauer, Thomas Klopstock, Claudia Stendel, Francisco Javier Rodríguez de Rivera Garrido, Ludger Schöls, Zofia Fleszar, Thomas Klockgether, Marcus Grobe‐Einsler, Ilaria Giordano, Myriam Rai, Massimo Pandolfo, Heike Jacobi, Ralf‐Dieter Hilgers, Jörg B. Schulz, Kathrin Reetz, on behalf of the EFACTS Study Group   +23 more
wiley   +1 more source

Optimization and Simulation of Extrusion Parameters in Polymer Compounding: A Comparative Study Using BBD and 3LFFD. [PDF]

Polymers (Basel)
Alsadi J.
europepmc   +1 more source

What scientific inferences can be made with randomized implementation rollout trials. [PDF]

Implement Sci
Brown CH, Smith JD, Haegerich T, Simon G, Cero I, Aarons G, Prado G, Wyman P, Kane J, Robinson D, Walunas TL, Zimmerman L, Vermeer W, Chin-Purcell L, McNulty M, Christopoulos KA, Garner B, McGovern M.   +17 more
europepmc   +1 more source

Advancing Severe Plastic Deformation for Tubular Samples: Systematic Review and Machine Learning Optimization

MetalMat, EarlyView.
This review highlights recent advancements in Severe Plastic Deformation (SPD) techniques tailored for tubular samples. The mechanisms of processing are critically discussed with emphasis on microstructural control and the governing process parameters that enable refinement to ultrafine‐ and nano‐grained structures. Comparative insights into equivalent
Eman M. Zayed, Abdulrahman I. Alateyah, Waleed H. El‐Garaihy, Mahmoud Shaban, Majed Alinizzi, Nahed A. El‐Mahallawy   +5 more
wiley   +1 more source

Measurement Error and Power in Family-Based Extensions to Mendelian Randomization. [PDF]

Behav Genet
Castro-de-Araujo LFS, Singh M, Zhou YD, Vinh P, Maes HHM, Verhulst B, Dolan CV, Neale MC.   +7 more
europepmc   +1 more source