Results 241 to 250 of about 42,514 (304)

Cross-cultural adaptation and psychometric validation of the Spanish version of the Orthorexia Nervosa Inventory (ONI-ES). [PDF]

Front Nutr
Hidalgo-Velez E, Onieva-Zafra MD, Hernández-Martínez A, Munera-Jareño M, Bermejo-Cantarero A, Parra-Fernández ML.   +5 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Psychometric evaluation of a multidimensional family resource assessment tool for schizophrenia (M-FRAT) from caregivers' perspectives in communities of Beijing, China. [PDF]

Front Psychiatry
Li T, Wang M, Pan Z, Chen L, Jin G, Lu X.   +5 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Measurement invariance and validation of the LPFS-BF 2.0 in clinical and community samples of Turkish adolescents. [PDF]

BMC Psychol
Coşkun F, Akça ÖF, Bilgiç A, Sharp C, Hutsebaut J.   +4 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Translation, cross-cultural adaptation, and psychometric evaluation of the Arabic version of the University of Wisconsin running injury and recovery index: a reliability and validity study. [PDF]

BMC Sports Sci Med Rehabil
Aljohani MMA, Alshehri YS, Shuwayhi AM, Alrais AA, Alsouhibani A, Heiderscheit B.   +5 more
europepmc   +1 more source

Cross-cultural adaptation and psychometric validation of the interdisciplinary digital literacy scale for medical students: the Turkish version (DLAD-TR). [PDF]

BMC Med Educ
Büyükdereli Atadağ Y, Saygılı T, Çelik Çoban A.   +2 more
europepmc   +1 more source

Editorial: Measuring vaccination perception, confidence, and uptake: advancing instrument development and validation. [PDF]

Front Public Health
Subramaniam DS, Bianco A, Subramaniam DP.   +2 more
europepmc   +1 more source