Results 111 to 120 of about 67,741 (269)
Exact-Factorization-Based Surface Hopping without Velocity Adjustment
While surface hopping has emerged as a powerful method for simulating non-adiabatic dynamics in large molecules, the ad hoc nature of the necessary velocity adjustments and decoherence corrections in the algorithm somewhat reduces its reliability.
Neepa T. Maitra (6333899) +2 more
core +1 more source
The factorization of đčâ [PDF]
Morrison, Michael A., Brillhart, John
openaire +3 more sources
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTENâdeficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana RondonâLorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCaâdirected therapies for glioblastoma treatment.
Kamila MaliszewskaâOlejniczak +4 more
wiley +1 more source
ACCOUNTING FOR PHASE CANCELLATIONS IN NON-NEGATIVE MATRIX FACTORIZATION USING WEIGHTED DISTANCES
(c)2014 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works for resale or ...
Ewert, S, Plumbley, MD, Sandler, M, IEEE
core
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROSâdependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The rutheniumâbased metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectinâmediated cytoskeletal organization, plecstatin inhibits anchorageâdependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Accelerated Multisecret Sharing Scheme Using Fast Matrix Spectral Factorization. [PDF]
Ăalkavur S, SolĂ© P, Ephremidze L.
europepmc +1 more source
Nanosecond infrared laser (NIRL) lowâvolume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Single circulating tumor cells (sCTCs) from highâgrade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source

