Results 91 to 100 of about 295,217 (268)
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Matrix factorization with Binary Components
Motivated by an application in computational biology, we consider low-rank matrix factorization with $\{0,1\}$-constraints on one of the factors and optionally convex constraints on the second one.
Hein, Matthias +2 more
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
On a variation of Sands' method
A subset of a finite additive abelian group G is a Z-set if for all a∈G, na∈G for all n∈Z. The group G is called Z-good if in every factorization G=A⊕B, where A and B are Z-sets at least one factor is periodic. Otherwise G is called Z-bad.
Evelyn E. Obaid
doaj +1 more source
3D Imaging of Rapidly Spinning Space Targets Based on a Factorization Method
Three-dimensional (3D) imaging of space targets can provide crucial information about the target shape and size, which are significant supports for the application of automatic target classification and recognition.
Yanxian Bi +3 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
On Twin Edge Colorings of Graphs
A twin edge k-coloring of a graph G is a proper edge coloring of G with the elements of Zk so that the induced vertex coloring in which the color of a vertex v in G is the sum (in Zk) of the colors of the edges incident with v is a proper vertex coloring.
Andrews Eric +4 more
doaj +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The Wiener–Hopf perspective on embedding formula: reusing solutions of boundary value problems
Embedding formula allows solutions to be reused within a family of boundary value problems by expressing a family of solutions in terms of a small number of solutions. Such formulas have been previously derived in the context of diffraction by applying a
Andrey I. Korolkov, Anastasia V. Kisil
doaj +1 more source

