Results 81 to 90 of about 67,741 (269)
Banach Spaces of Analytic Vector-valued Functions [PDF]
The main theme of the thesis is the study of continuity and approximation problems, involving matrix-valued and vector-valued Hardy spaces on the unit disc ID and its boundary T in the complex plane.
Barclay, Steven John
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Attributes coupling based matrix factorization for item recommendation
Recommender systems have attracted lots of attention since they alleviate the information overload problem for users. Matrix factorization is one of the most widely employed collaborative filtering techniques in the research of recommender systems due to
Yang Gao +7 more
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Online Kernel Matrix Factorization [PDF]
. The problem of effciently applying a kernel-induced feature space factorization to a large-scale data sets is addressed in this thesis. Kernel matrix factorization methods have showed good performances solving machine learning and data analysis ...
Páez Torres, Andrés Esteban
core
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Outlier detection in video sequences under affine projection
A novel robust method for outlier detection in structure and motion recovery for affine cameras is presented. It is an extension of the well-known Tomasi-Kanade factorization technique (C. Tomasi T. Kanade, 1992) designed to handle outliers.
Heyden, A., Huynh, D.Q.
core

