Results 121 to 130 of about 11,649,749 (258)
Abnormal Traffic Detection Method Based on ME-PGNMF [PDF]
Jisuanji gongcheng, 2018 Because some network anomalies have little effect on traffic flow,it is difficult to find such anomalies in traffic analysis.Traditional anomaly traffic detection method based on Principal Component Analysis(PCA) is not suitable for continuous local ...
CHEN Lulu,GUO Wenpu,HE Hao
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Factorization method using interpolated feature tracking via projective geometry
, 2003 The factorization method by Tomasi and Kanade simultaneously recovers camera motion and object shape from an image sequence. This method is robust because the solution is linear by assuming the orthographic camera model.
H. Saito +3 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Attributes coupling based matrix factorization for item recommendation
, 2017 Recommender systems have attracted lots of attention since they alleviate the information overload problem for users. Matrix factorization is one of the most widely employed collaborative filtering techniques in the research of recommender systems due to
Yang Gao +7 more
core +1 more source
Indicator Regularized Non-Negative Matrix Factorization Method-Based Drug Repurposing for COVID-19. [PDF]
Front Immunol, 2020 Tang X +5 more
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Exact-Factorization-Based Surface Hopping without Velocity Adjustment
While surface hopping has emerged as a powerful method for simulating non-adiabatic dynamics in large molecules, the ad hoc nature of the necessary velocity adjustments and decoherence corrections in the algorithm somewhat reduces its reliability.
Neepa T. Maitra (6333899) +2 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source