A Probabilistic Matrix Factorization Method for Identifying lncRNA-disease Associations. [PDF]
Xuan Z +5 more
europepmc +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
RCMF: a robust collaborative matrix factorization method to predict miRNA-disease associations. [PDF]
Cui Z, Liu JX, Gao YL, Zheng CH, Wang J.
europepmc +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
On one method of factorization of polynomials
Запропоновано та обгрунтовано чисельний метод розкладу многочлена з комплексними коефіцентами на множники. Побудовано алгоритм розкладу многочлена з дійсними коефіцієнтами на дійсні множники у випадку кратних коренів.We propose and justify a numerical ...
Джалладова, И.А.
core +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
TriTan: an efficient triple nonnegative matrix factorization method for integrative analysis of single-cell multiomics data. [PDF]
Ma X, Lin L, Zhao Q, Iqbal M.
europepmc +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Source Apportionment of Potentially Toxic Elements in Agricultural Soils of Yingtan City, Jiangxi Province, China: A Principal Component Analysis-Positive Matrix Factorization Method. [PDF]
Chen S, Wang H, Han R.
europepmc +1 more source
L2,1-GRMF: an improved graph regularized matrix factorization method to predict drug-target interactions. [PDF]
Cui Z, Gao YL, Liu JX, Dai LY, Yuan SS.
europepmc +1 more source

