Results 151 to 160 of about 14,368 (309)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Compact Factorization of Matrices Using Generalized Round-Rank [PDF]
, 2018 Matrix factorization is a popular machine learning technique, with applications in variety of domains, such as recommendation systems [16, 28], natural language processing [26], and computer vision [10].
Pezeshkpour, Pouya
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
A Constrained Sparse Algorithm for Nonnegative Matrix Factorization
工程科学与技术, 2015 :Aiming at the lack of sparseness of factorization matrix in the nonnegative matrix factorization (NMF) algorithm,a new constrained NMF algorithm was proposed.A sparseness constraint was added to the original nonnegative matrix factorization (NMF ...
李臣明, 张师明, 李昌利
doaj
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Factorization of matrices into quadratic ones. III
Linear Algebra and its Applications, 1995 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Hyperbolic QR factorization for J-spectral factorization of polynomial matrices
, 2004 Motivated by a superfluous zero extraction problem arising in the discrete-time J-spectral factorization of polynomial matrices, we propose an algorithmic solution to hyperbolic QR factorization of a rank deficient constant matrix.
Didier Henrion, Peter Hippe
core
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source