Results 131 to 140 of about 35,564,439 (374)

Review of Inheritance as a Factor in Criminality. A study of 1000 cases of young repeated offenders. [PDF]

, 1914
Robert H. Gault
openalex   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

EDI3 knockdown in ER-HER2+ breast cancer cells reduces tumor burden and improves survival in two mouse models of experimental metastasis

Breast Cancer Research
Background Despite progress understanding the mechanisms underlying tumor spread, metastasis remains a clinical challenge. We identified the choline-producing glycerophosphodiesterase, EDI3 and reported its association with metastasis-free survival in ...
Annika Glotzbach, Katharina Rohlf, Anastasia Gonscharow, Simon Lüke, Özlem Demirci, Brigitte Begher-Tibbe, Nina Overbeck, Jörg Reinders, Cristina Cadenas, Jan G. Hengstler, Karolina Edlund, Rosemarie Marchan   +11 more
doaj   +1 more source

CHARACTERIZATION OF LEUKIN: AN ANTIBACTERIAL FACTOR FROM LEUCOCYTES ACTIVE AGAINST GRAM-POSITIVE PATHOGENS [PDF]

, 1956
Robert C. Skarnes, Dennis W. Watson
openalex   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Somatosensory Response to Trigeminal Stimulation: A Functional Near-Infrared Spectroscopy (fNIRS) Study

Scientific Reports, 2018
Functional near-infrared spectroscopy (fNIRS) is an optical imaging technique measuring relative hemodynamic changes in superficial cortical structures. It has successfully been applied to detect a hemodynamic response in the somatosensory cortex evoked ...
Christine I. Hucke, Marlene Pacharra, Jörg Reinders, Christoph van Thriel   +3 more
doaj   +1 more source

VITAMIN K, AN ESSENTIAL FACTOR FOR THE PHOTOCHEMICAL ACTIVITY OF ISOLATED CHLOROPLASTS [PDF]

, 1958
Norman I. Bishop
openalex   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Points Regarding the «Time Factor» in Roentgen Irradiation with Divided Dosage [PDF]

, 1946
Hugo Ahlbom
openalex   +1 more source

The association between hair cortisol and burnout is moderated by age, psychosocial, and immunological markers

Brain, Behavior, & Immunity - Health
Background: Exhaustion and depersonalization are the core symptoms of the occupational burnout. However, burnout is not an all-or-nothing phenomenon, but can occur in a milder to moderate form in otherwise healthy employees.
Patrick D. Gajewski, Peter Bröde, Maren Claus, Klaus Golka, Jan G. Hengstler, Carsten Watzl, Edmund Wascher, Stephan Getzmann   +7 more
doaj