Results 121 to 130 of about 15,541,552 (290)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Evaluation of Ohio Department of Transportation roadway/weather sensor systems for snow and ice removal operations. Part I, RWIS

open access: yes, 2003
"June 2003."; Includes bibliographical references (p. 107-113).; Final report.; Performed by Human Factors and Ergonomics Laboratory, Ohio Research Institute for Transportation and the Environment for Ohio Dept.
Zwahlen, Helmut T.   +1 more
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Connecting Pathogen Transmission and Performance of the WHO’s ‘My 5 Moments of Hand Hygiene’ in a High-Fidelity Simulation

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
Background: The World Health Organization launched ‘Your 5 moments for hand hygiene’ to identify when healthcare workers should perform hand hygiene to reduce healthcare-associated infections (HAIs).
Paige Gannon   +9 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Synchronization-based fusion of EEG and eye blink signals for enhanced decoding accuracy

open access: yesScientific Reports
Decoding locomotor tasks is crucial in cognitive neuroscience for understanding brain responses to physical tasks. Traditional methods like EEG offer brain activity insights but may require additional modalities for enhanced interpretative precision and ...
Emad Alyan   +3 more
doaj   +1 more source

Occupational ergonomics risk factors prioritization using integrated analytical hierarchy process (AHP) approach: a study of a local automotive component manufacturer [PDF]

open access: yes, 2019
There is a need to support the occupational safety and health (OSH) practitioners defining their priorities action for improving working environment condition and minimizing the risk factors in the early stage of development.
Fazilah, Abdul Aziz   +2 more
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Physical ergonomics, oil and gas, processing equipment, task analysis

open access: yes, 2020
Maintenance of offshore processing equipment is among critical aspects during design stages due to inevitable human intervention while performing the task.
JawatanKuasa Kerja PSM Human Factors and Ergonomics Society Malaysia
core  

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