Results 201 to 210 of about 25,027,958 (329)

Evidence on the Reasons and Factors Influencing Contraceptive Nonutilization Among Women of Childbearing Age in Suburban Setting in Sub-Saharan Africa: A Scoping Review. [PDF]

Nurs Health Sci
Baloyi TV, Madela-Mntla E, Duah E, Maluleke K, Kgarosi K, Pieters J, Mashamba-Thompson T.   +6 more
europepmc   +1 more source

A network of jasmonate‐responsive bHLH factors modulate monoterpenoid indole alkaloid biosynthesis in Catharanthus roseus [PDF]

, 2017
Barunava Patra, Sitakanta Pattanaik, Craig Schluttenhofer, Ling Yuan   +3 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

“There's No Pamphlet for the Kind of Sex I Have”: HIV-Related Risk Factors and Protective Behaviors Among Transgender Men Who Have Sex With Nontransgender Men

, 2009
Jae Sevelius
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Prediction of risk factors for postpartum stress urinary incontinence based on pelvic floor ultrasound combined with clinical information. [PDF]

SAGE Open Med
Chen Y, Zhang T.
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Associations of Diabetes, Smoking, and Metabolic Factors With the Risk of Breast and Prostate Cancers: A Population-Based Retrospective Cohort Study. [PDF]

Cancer Med
Yau STY, Hung CT, Leung EYM, Lee A, Yeoh EK.   +4 more
europepmc   +1 more source

Effect of Yoga on Pain, Brain‐Derived Neurotrophic Factor, and Serotonin in Premenopausal Women with Chronic Low Back Pain [PDF]

, 2014
Moseon Lee, Woongjoon Moon, Jaehee Kim
openalex   +1 more source