Results 91 to 100 of about 6,776,466 (294)
Context: Tuberculosis (TB) and diabetes mellitus (DM) remains a worldwide global public health problem. About 95% of patients with TB live in the low and middle-income countries and more than 70% of patients with DM also live in the same countries ...
Vivek Nagar +5 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Infantile esotropia: risk factors associated with reoperation
Adriano Magli,1 Luca Rombetto,2 Francesco Matarazzo,2 Roberta Carelli1 1Department of Ophthalmology, Orthoptics and Pediatric Ophthalmology, University of Salerno, Salerno, 2Department of Ophthalmology, Federico II University, Naples, Italy Abstract ...
Magli A +3 more
core
Clinical Manifestations and Risk Factors of Tigecycline-Associated Thrombocytopenia
Yuanchao Zhu, Fei Zhao, Pengfei Jin Department of Pharmacy, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Key Laboratory of Assessment of Clinical Drugs Risk and Individual
Zhu Y, Zhao F, Jin P
core
BackgroundThe desire to have children can become a significant consideration for many people living with HIV (PLHIV), both men and women, particularly as access to antiretroviral therapy (ART) increases and rates of mother-to-child transmission (MTCT ...
Abel Endawkie +3 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Prevalence of Obesity and Associated Risk Factors among Adults in Kinondoni Municipal District, Dar es Salaam Tanzania. [PDF]
Obesity is on the rise worldwide, not sparing developing countries. Both demographic and socio-economic factors play parts in obesity causation. Few surveys have been conducted in Tanzania to determine the magnitude of obesity and its association with ...
Mugusi, Ferdinand M +5 more
core +1 more source
Background Delayed entry into HIV care has complicated the challenges faced in sub-Saharan Africa due to the high HIV burden. A clear knowledge of the factors affecting delayed entry will be essential in directing interventions towards reducing delayed ...
Noah F. Takah +5 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

