Results 81 to 90 of about 6,776,466 (294)

Odds and associated factors for thrombosis development among Lebanese COVID-19 patients: a case–control retrospective study

Journal of Pharmaceutical Policy and Practice
Background Thromboembolism is reported to be up to 27% in COVID-19 patients due to SARS-CoV-2 infection. Dysregulated systemic inflammation and various patient traits play a vital role in thrombosis progression.Purpose To assess odds and associated ...
Mahmoud Youness, Sara Mansour, Fouad Sakr, Samer Olabi, Sarah Atwi, Iman Younes Martinez, Sami El Khatib, Souheil Hallit, Pascale Salameh, Diana Malaeb, Hassan Hosseini   +10 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Organizational factors associated with supply chain management performance

, 2018
The concept of supply chain management (SCM) is receiving greater attention among academics and organizations and is viewed as a potential source of bottom and top-line growth. Despite the potential for improving organizational performance through supply
Bell, Gregory A.
core  

Factors Associated with Breastfeeding Practice in Indonesia

, 2020
The fact is that practice of giving exlusive breastfeeding has not reached favorable numberin some developing countries because of various factors This study aims to determine the relationship between the level of education of mothers the occupation of
Sindung Haryanto, Dominica Chyta Asthyka
core  

Prevalence of Sarcopenic Obesity and Associated Factors in Older Adults [PDF]

Aim: Sarcopenia is a significant contributor to morbidity and mortality, with unfavorable consequences. The present study investigated the prevalence of sarcopenia associated with obesity, referred to as sarcopenic obesity, and the associated factors ...
Meris Esra Bozkurt, Tuba Olcay Vardal
core   +1 more source

A Survey on the Status Quo and Influencing Factors of Health-Related Quality of Life Among Family Caregivers of People with Dementia: A Cross-Sectional Study

International Journal of General Medicine
Hongli Liu,1,2,* Tengfei Niu,3,* Jiajia Chen,2,4 Zhenyu Wu,5 Taowu Gong,5 Pengcheng Zhao,5 Yuhang Zhu,6 Li Zhang2,7 1Department of Intensive Care Unit, Chongqing General Hospital, Chongqing University, Chongqing, 401147, People’s Republic of ...
Liu H, Niu T, Chen J, Wu Z, Gong T, Zhao P, Zhu Y, Zhang L   +7 more
doaj  

Knowledge and Awareness of Rheumatoid Arthritis among the Population of Al Qunfudhah, Saudi Arabia: A Cross-sectional Study

Annals of Rheumatology and Autoimmunity
Introduction: Rheumatoid arthritis (RA), a chronic autoimmune ailment, incites inflammation and degradation of joint synovium, predominantly impacting hands, wrists, and knees.
Hassan Ali Alzubaidi, Medhat Fotoh Taha, Ali Nori Alfaqih, Waleed Hafiz, Ahmed Ali Alhayli, Hassan Mohmmed Alfaqih, Mohammed Hussain Alothayqi, Mohammed Ali Alfaqih, Khalid Abdullah Alfaqih, Ali Abdullah Alsayed   +9 more
doaj   +1 more source

Knowledge, practice and associated factors of infection prevention among healthcare workers in Debre Markos referral hospital, Northwest Ethiopia

BMC Health Services Research, 2018
Background Healthcare-associated infections are a major global public health agenda. Health care workers are front line of protecting themselves and clients from infection. This study examined the knowledge and practice of healthcare workers on infection
Melaku Desta, Temesgen Ayenew, Nega Sitotaw, Nibretie Tegegne, Muluken Dires, Mulualem Getie   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source