Results 131 to 140 of about 9,174,632 (257)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

A Study of Factors Influencing Mothers' Willingness to Become Breast Milk Donors: Scoping Review

open access: yesJournal of Nursing Practice
Background: Breast milk donation is a practice that provides significant benefits to premature infants and infants with certain medical conditions. However, mothers' willingness to donate breastmilk is still influenced by various factors, including ...
Sri Annisapada Jamaru   +2 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Factors influencing exacerbation-related self-management in patients with COPD: a qualitative study

open access: yes, 2016
YJG Korpershoek,1,2 SCJM Vervoort,3 LIT Nijssen,2 JCA Trappenburg,2 MJ Schuurmans1,2 1Research Group Chronic Illnesses, Faculty of Health Care, University of Applied Sciences Utrecht, 2Julius Center for Health Sciences and Primary Care, University ...
Nijssen LIT   +4 more
core  

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

The status and influencing factors of xerostomia in maintenance hemodialysis patients

open access: yesLinchuang shenzangbing zazhi, 2019
Objective To investigate the status and influencing factors of xerostomia in maintenance hemodialysis( MHD) patients. Methods A random sampling method was used to select 114 patients with MHD from September to October of 2017 in Grade 3 A Hospital of ...
LI A-min   +4 more
doaj  

Psychological Factors Influencing Appearance Anxiety Among Adolescents: A Systematic Literature Review [PDF]

open access: yes
Bernadette Btari Kania Putri, Afra Hafny Noer, Fredrick Dermawan Purba Department of Psychology, Faculty of Psychology, Universitas Padjadjaran, Jatinangor, West Java, IndonesiaCorrespondence: Bernadette Btari Kania Putri, Email bernadette20002@mail ...
Purba FD, Noer AH, Putri BBK
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

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