Results 141 to 150 of about 9,174,632 (257)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Factors Influencing the Selection of Precision Farming Information Sources by Cotton Producers [PDF]

Precision farming information demanded by cotton producers is provided by various suppliers, including consultants, farm input dealerships, University Extension systems, and media sources. Factors associated with the decisions to select among information
Roberts, Roland K., Martin, Steven W., English, Burton C., Larson, James A., Lambert, Dayton M., Jenkins, Amanda, Velandia, Margarita M.   +6 more
core  

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Exploring the state and influential factors of dental caries in preschool children aged 3–6 years in Xingtai City

BMC Oral Health
Objective To explore the main factors affecting early dental caries among preschool children aged 3–6 years in Xingtai City to formulate effective preventive measures. Methods A cross-sectional study was conducted on 570 preschool children aged 3–6 years
Hua Xu, Xiaolan Ma, Junrong Wang, Xuefang Chen, Qian Zou, Jiandong Ban   +5 more
doaj   +1 more source

Clinical factors influencing resilience in patients with anorexia nervosa

, 2019
Chikako Kane,1 Masahito Tomotake,2 Sayo Hamatani,3 Shinichi Chiba,2 Naomi Kameoka,4 Shinya Watanabe,4 Masahito Nakataki,4 Shusuke Numata,4 Tetsuro Ohmori4 1Department of Nursing, Tokushima University Hospital, Tokushima-shi, Tokushima, Japan ...
Ohmori T, Watanabe S, Nakataki M, Kane C, Tomotake M, Hamatani S, Kameoka N, Chiba S, Numata S   +8 more
core  

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

An Empirical Study on Factors influencing Apparel Brand Loyalty among Malaysian Women

, 2020
The apparel industry is a very competitive industry. In Malaysia, the apparel industry consists of players from both the international and local brand. Due to the high competition, it is critical to attract and retain loyal customers.
Angusamy, Ajitha, Kuppusamy, Jayanty, Teo, Kai Ting, Balakrishnan, Kavitha   +3 more
core