Results 91 to 100 of about 3,331,363 (306)
FUZZY SECOND ORDER SLIDING MODE CONTROL OF A UNIFIED POWER FLOW CONTROLLER
Electrical engineering & Electromechanics, 2019 Purpose. This paper presents an advanced control scheme based on fuzzy logic and second order sliding mode of a unified power flow controller. This controller offers advantages in terms of static and dynamic operation of the power system such as the ...
Abdellatif Hinda +2 more
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
California Physician Facts and Figures [PDF]
, 2010 Examines trends in the state's supply of primary care physicians, including demographics, specialties, and education and training; acceptance of new patients by coverage type; family and general practitioner compensation; and medical group ...
Craig Paxton
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Health and Wellness: Black Facts [PDF]
, 2015 Every year approximately 85,000 African American deaths are attributed to the Black – White mortality gap. Racial disparities in health in the United States are substantial. Today, death rates for African Americans remain 40% higher than for whites. They
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NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Facts, Formal Objects and Ontology [PDF]
, 2009 What is a fact ? Are there such things
Mulligan, Kevin
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Canadian Medical Association Journal, 2012 No matter how much you know, you never know all the facts. Juggling facts pervades all parts of medicine. In particular, we seem to love the little contraindications. “You can’t take more than 2 litres off in a thoracentesis before you run the risk of re-expansion pulmonary edema ...
openaire +1 more source