Results 81 to 90 of about 631,339 (315)

Creating Killer Facts and Graphics [PDF]

open access: yes, 2019
‘Killer facts’ are those punchy, memorable, headline-grabbing statistics that make reports special. They cut through the technicalities to fire people up about changing the world.
Green, Duncan
core  

FUZZY SECOND ORDER SLIDING MODE CONTROL OF A UNIFIED POWER FLOW CONTROLLER

open access: yesElectrical engineering & Electromechanics, 2019
Purpose. This paper presents an advanced control scheme based on fuzzy logic and second order sliding mode of a unified power flow controller. This controller offers advantages in terms of static and dynamic operation of the power system such as the ...
Abdellatif Hinda   +2 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

'Facts' and 'Statements of Fact'

open access: yesThe University of Chicago Law Review, 1937
This language is similar to that of the corresponding section of the New York Civil Practice Act, but differs-and this is the interesting point -in that all reference to 'facts' is omitted. To bring out the difference it will be helpful to quote the section of the New York Act, italicizing the part which refers to 'facts.' The New York provision reads:
openaire   +2 more sources

The Facts Are Incomplete [PDF]

open access: yesDeutsches Ärzteblatt international, 2012
In the article, the example case that was to be assessed, the patient’s advance directive was not fully reported. What is missing is any information on whether, according to the text of the patient’s advance directive, life preserving measures should be suspended in principle as soon as the patient is in a coma—that is, irrespective of whether a chance
openaire   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Robust Stylized Facts on Comovement for the Spanish Economy [PDF]

open access: yes
In this article we further develop the suggestion of obtaining stylized facts on comovement on the basis of prewhitened time series proposed in André, Pérez and Martín (2002). Firstly, we show some examples on the robustness of the method.
Javier J. Pérez, Francisco J. André
core  

Hypotheses and facts [PDF]

open access: yesPhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2001
The book, The river , is based on assumptions and not facts. Oral polio vaccine was produced entirely in rhesus monkey kidney cell cultures. Allegations that it was produced in chimpanzee kidneys at the Wistar Institute in Philadelphia or, alternatively, that the vaccine was made in the then Belgian Congo in ...
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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