Results 31 to 40 of about 631,339 (315)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
TapuyaHow do algorithms shape the experience of facts? Drawing on ethnographic fieldwork in Limón, Costa Rica, this paper explores the role of algorithms in mediating three kinds of “factishes”: data truths, affective facts, and mystic revelations. The article
Ignacio Siles +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
IFPRI key facts series: Food and nutrition security
, 2022 This is a second Food and Nutrition Key Facts sheet in a series of Key Facts sheets that IFPRI is producing based on Integrated Household Surveys (IHS).
Banda, Chimwemwe +1 more
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Facts, Concepts and Patterns of Life—Or How to Change Things with Words
Philosophies, 2023 In his last writings, Wittgenstein repeatedly addresses the question of how our concepts relate to general facts of nature or human nature and how they are embedded in our lives.
Jasmin Trächtler
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Facts, Alternative Facts, and Fact Checking in Times of Post-Truth Politics [PDF]
SSRN Electronic Journal, 2017 Abstract How effective is fact checking in countervailing “alternative facts,” i.e., misleading statements by politicians? In a randomized online experiment during the 2017 French presidential election campaign, we subjected subgroups of 2480 French voters to alternative facts by the extreme-right candidate, Marine Le Pen, and/or corresponding facts ...
Barrera, Oscar +3 more
openaire +4 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Evidentiary Reasoning and Artificial Intelligence in the Assessment of the Judicial Proof
Opinión Jurídica, 2022 This article shows a structured process through the use of the “Intelligent Judge” expert system, to assist judges in the construction of inferences or evidentiary arguments based on the evidence, facts, and hypotheses or allegations that are considered ...
Orion Vargas Vélez +1 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Social constructivism and its implications for critical media studies [PDF]
Conflict & Communication Online, 2006 While media critics maintain that war coverage has a strong bias toward promoting conflict escalation, their opponents claim that the concept of distorted reality cannot be upheld.
Wilhelm Kempf
doaj