Results 41 to 50 of about 364,498 (267)
The Subject, Object and the Duty to Provide Evidence
In our usual language, the word “evidence” represents the mental and logical operation by which we attempt to prove something, to demonstrate, to emphasize a statement that provides credibility to a certain situation.
Cristinel-Ioan Murzea
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
It is shown that the use of controlled shunt reactors enables, based on ultra-high voltage transmission lines, to create a controlled generation of new generation FACTS types that meet the requirements of modern power systems and combinations.
В.В. Кучанський +1 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Between Documentary and Provocation. New Tendencies (not only) in Contemporary Polish Holocaust Literature [PDF]
The Holocaust can be seen as a transnational crime, and a collective trauma of universal extension. Therefore national approaches could be seen only as an example out of many others.
Hans-Christian Trepte
doaj
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Post-Truth Era and Fake News
Post-Truth Era is a term used recently by The Oxford Dictionary and it deals with facts have no much importance in our current world. People show no interest to know the truth and they believe what match their interests and desires.
Farah Hasan, Sanaa Hassan
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Has Latour Real-ly Unravelled the Real: The Journey from Laboratory Life to Down to Earth?
This article traces Bruno Latour’s answer to the question ‘what is real?’ from Latour and Steve Woolgar in Laboratory Life: The Social Construction of Scientific Facts (1979) through to Latour in Down to Earth: Politics in the New Climate Change (2018 ...
Charles Lawson
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source

