Results 81 to 90 of about 3,315,315 (285)

Opioid Addiction 2016 Facts & Figures [PDF]

open access: yes, 2016
National Opioid Overdose Epidemic* Drug overdose is the leading cause of accidental death in the US, with 55,403 lethal drug overdoses in 2015. Opioid addiction is driving this epidemic, with 20,101 overdose deaths related to prescription pain relievers,

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Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Multi-Type FACTS Controllers for Power System Compensation: A Case Study of the Nigerian 48-Bus, 330 kV System

open access: yesNigerian Journal of Technological Development, 2021
Flexible alternating current transmission system (FACTS) devices have provided proficient answers to power system instabilities faced in the systems operations today with very little infrastructural investment fund. This paper investigates the effects of
I. E. Nkan, E. E. Okpo, O. I. Okoro
doaj  

California Hospital Facts and Figures [PDF]

open access: yes, 2010
Provides statistics on the state's general acute care facilities, including bed supply and capacity, geographic distribution, ownership type, utilization, and financial health.

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Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

FUZZY SECOND ORDER SLIDING MODE CONTROL OF A UNIFIED POWER FLOW CONTROLLER

open access: yesElectrical engineering & Electromechanics, 2019
Purpose. This paper presents an advanced control scheme based on fuzzy logic and second order sliding mode of a unified power flow controller. This controller offers advantages in terms of static and dynamic operation of the power system such as the ...
Abdellatif Hinda   +2 more
doaj   +1 more source

Neutrino masses: From fantasy to facts [PDF]

open access: yes, 1999
Theory suggests the existence of neutrino masses, but little more. Facts are coming close to reveal our fantasy: solar and atmospheric neutrino data strongly indicate the need for neutrino conversions, while LSND provides an intriguing hint. The simplest
A. Dar   +111 more
core   +3 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Health and Wellness: Black Facts [PDF]

open access: yes, 2015
Every year approximately 85,000 African American deaths are attributed to the Black – White mortality gap. Racial disparities in health in the United States are substantial. Today, death rates for African Americans remain 40% higher than for whites. They

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