Amplitude and frequency encoding result in qualitatively distinct informational landscapes in cell signaling [PDF]
Cells continuously sense their surroundings to detect modifications and generate responses. Very often changes in extracellular concentrations initiate signaling cascades that eventually result in changes in gene expression. Increasing stimulus strengths
Alan Givré +2 more
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Beyond Tanimoto: a learned bioactivity similarity index enhances ligand discovery [PDF]
Structural similarity metrics such as the Tanimoto coefficient (TC) miss many functionally related compounds—indeed, 60% of similarly bioactive ligand pairs in the ChEMBL database show TC < 0.30, revealing a major blind spot that constrains ligand ...
Gustavo Schottlender +6 more
doaj +2 more sources
Disponibilidad, acceso y características de las tesis en la Facultad de Ingeniería y en la Facultad de Ciencias Exactas y Naturales de la Universidad de Buenos Aires = Availability, Access, and Characteristics of the Theses in the Facultad de Ingeniería and the Facultad de Ciencias Exactas y Naturales of the Universidad de Buenos Aires [PDF]
Se intenta reflejar la disponibilidad de las tesis y trabajos equivalentes para acceder a títulos de grado y de postgrado en las Facultades de Ingeniería y de Ciencias Exactas y Naturales de la Universidad de Buenos Aires (UBA), así como las ...
María Alejandra Plaza
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Fruit‐Penetrating Ability is Associated With the Number of Modified Lateral Bristles in the Ovipositor of Drosophila suzukii [PDF]
In some insects, the evolution of herbivory was facilitated by the acquisition of specialized structures that confer adaptive advantages, allowing access to new ecological niches. A notable evolutionary innovation in Drosophila suzukii is the ovipositor,
Madelein Sara Micaela Ortiz +6 more
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Temporal and Spatial Patterns of Mating in Rhodnius prolixus [PDF]
The kissing bug Rhodnius prolixus is a nocturnal species; however, its temporal mating patterns remain unexplored. Copulation lasts about fifty minutes, during which time the couple remains almost motionless. We hypothesized that R.
Franco Divito +3 more
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Bovine Serum Albumin Nanoparticle-Mediated Delivery of Ribavirin and Mycophenolic Acid for Enhanced Antiviral Therapeutics [PDF]
The global spread of viral diseases is a public health issue. Ribavirin (RBV) and mycophenolic acid (MPA) are well-known wide-spectrum antiviral agents.
Mayra A. Castañeda Cataña +7 more
doaj +2 more sources
Live and let die: signaling AKTivation and UPRegulation dynamics in SARS-CoVs infection and cancer
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen responsible for the coronavirus disease 2019 (COVID-19) pandemic. Of particular interest for this topic are the signaling cascades that regulate cell survival and death, two
Mariana Suaya +6 more
doaj +1 more source
Author Correction: A new tool to sense pH changes at the neuromuscular junction synaptic cleft
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Matías Blaustein +7 more
doaj +1 more source
In this study we explored how picoplankton community structure and diversity varied along three cascade oligo-mesotrophic reservoirs of the Limay River (Patagonia, Argentina): Alicura, Piedra del Águila and Ramos Mexía.
M. Carolina Bernal +8 more
doaj +1 more source
Alterations of myeloid cell populations have been reported in patients with tuberculosis (TB). In this work, we studied the relationship between myeloid-derived suppressor cells (MDSC) and monocytes subsets with the immunological responsiveness of TB ...
Nicolás O. Amiano +22 more
doaj +1 more source

