ABSTRACT Objective Autosomal dominant progranulin (GRN) pathogenic variants are a genetic cause of frontotemporal lobar degeneration. Though clinical trials for GRN‐related therapies are underway, there is an unmet need for biomarkers that can predict symptom onset and track disease progression.
Taru M. Flagan+46 more
wiley +1 more source
Correction to: The Effect of Biopsychosocial-Spiritual Factors on Medication Adherence in Chronic Diseases in Türkiye. [PDF]
Bilgin A+3 more
europepmc +1 more source
ASSOCIATION NEWS GIFT TO THE FACULTY OF ANÆSTHETISTS [PDF]
Geoffrey Organe, Bernard Johnson
openalex +1 more source
Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities
Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski+13 more
wiley +1 more source
Advancing Transgender Health Education for Health Professional Students: A Faculty Fellowship Model for Capacity Building and Curricular Change. [PDF]
Linsenmeyer WR+10 more
europepmc +1 more source
ABSTRACT The pathogenesis of Sydenham chorea remains unclear. We report a 10‐year‐old girl presenting with subacute chorea and mild carditis following Streptococcal throat infection. Single‐cell RNA sequencing on 30,794 peripheral immune cells from the patient and two sex‐matched controls revealed nine immune cell clusters.
Velda X. Han+9 more
wiley +1 more source
Comparison of Standard Setting Procedures to Establish Defensible Passing Standards for Clinical Skills Assessment: Angoff, Borderline Group, Contrasting Groups and Patient Safety Methods. [PDF]
Tappan RS+4 more
europepmc +1 more source
Frequency of Seroconversion in Aquaporin‐4 Antibody Testing: Insights From Real‐World Data
ABSTRACT Clinicians often repeat aquaporin‐4‐immunoglobulin G (AQP4‐IgG) testing in case of possible seroconversion. Compared with older, less sensitive immunofluorescence assays (IFA), cell‐based assays (CBA) offer higher sensitivity. This study assessed the frequency of seroconversion in a retrospective Cleveland Clinic cohort (2006–2024) of 451 ...
Tatchaporn Ongphichetmetha+5 more
wiley +1 more source
Interpretations on Chat Generative Pre-training Transformer vs. surgeons on pancreatic cancer queries: accuracy and empathy evaluated by patients and experts. [PDF]
Sengul I, Sengul D.
europepmc +1 more source