Results 61 to 70 of about 3,939,764 (351)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Changing Future Faculty's Conceptions of SoTL

International Journal for the Scholarship of Teaching and Learning, 2019
Preparing Future Faculty (PFF) programs provide graduate students across all disciplines with professional development that addresses a range of faculty responsibilities.
Darryl Reano, Stephanie Masta, Jon Harbor   +2 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Bridging the gap: a cross-sectional study on biomedical waste management education and compliance in dental institutions of Delhi National Capital Region

GMS Hygiene and Infection Control
Introduction and method: Biomedical waste management (BMWM) ensures the safe handling, segregation, and disposal of healthcare waste from hospitals, clinics, and laboratories. It reduces infection risks, protects public health, and promotes environmental
Mahesh, Shakila, Hemalata, Kruthiventi, Shanta, Ramya, Vashistha, Urvi, Krishnakumar, Kavya, Arora, Samridhi, Gupta, Alpa   +6 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

From On-Campus to Online: A Trajectory of Innovation, Internationalization and Inclusion

International Review of Research in Open and Distributed Learning, 2016
This paper presents a study focused on a trajectory for developing an online operating mode on a campus-based university in the area of Massachusetts, USA.
Darlinda Pacheco Moreira
doaj   +1 more source

Institutional and programmatic determinants for graduate public affairs’ online education: Assessing the influence of faculty workload [PDF]

, 2021
Bruce L. Blair, Derek R. Slagle, Adam M. Williams   +2 more
openalex   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Boosting scientific community values: The impact of social inclusion interventions on biomedical instructors

Journal of Clinical and Translational Science
Interventions to foster inclusive learning environments may benefit college STEMM instructors (NASEM, 2019). We investigated the impact of a social inclusion intervention (SII) on scientific self-efficacy, identity, community values, and persistence ...
Paul R. Hernandez, Wenyi Du, Cristian Cervantes Aldana, Nichole A. Broderick, Jo Handelsman, Hyewon Lee, Linlin Luo, Natalia Maldonado, Holly A. Miller, Sarah Miller, Megan Patterson, Rachelle Pedersen, Perla Sandoval, Janice Vong, Mica Estrada   +14 more
doaj   +1 more source