Results 61 to 70 of about 7,997,916 (358)

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

Assessing the interactivity and prescriptiveness of faculty professional development workshops: The Real-Time Professional Development Observation Tool (R-PDOT) [PDF]

open access: yes, 2016
Professional development workshops are one of the primary mechanisms used to help faculty improve their teaching, and draw in many STEM instructors every year. Although workshops serve a critical role in changing instructional practices within our community, we rarely assess workshops through careful consideration of how they engage faculty.
arxiv   +1 more source

Where teachers are few: documenting available faculty in five Tanzanian medical schools. [PDF]

open access: yes, 2016
BACKGROUND:Faced with one of the lowest physician-to-population ratios in the world, the Government of Tanzania is urging its medical schools to train more physicians.
Goodell, Alex J   +3 more
core   +2 more sources

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha   +6 more
wiley   +1 more source

Creating a Cross-Campus Peer Mentor Network

open access: yesJournal of College Orientation, Transition, and Retention, 2012
This article provides specific best practices for creating a cross-campus peer mentor network. Peer mentoring programs are proliferating on college campuses, especially those that are focused on helping first-year students as they transition into a ...
Kayla Lisenby
doaj   +1 more source

Barriers to Active Learning for Computer Science Faculty [PDF]

open access: yesarXiv, 2018
Active learning is a proven pedagogical style that has demonstrated value by improving students' performance and classroom experience. In spite of the evidence, adoption of active learning in computer science remains relatively low. To identify what barriers to adoption exist, an electronic survey was sent to 369 computer science faculty in a state in ...
arxiv  

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

mSphere of Influence: Hiring of Underrepresented Minority Assistant Professors in Medical School Basic Science Departments Has a Long Way To Go

open access: yesmSphere, 2019
Michael D. L. Johnson is a molecular microbiologist observing the role of metals in bacterial biology. In this mSphere of Influence article, he discusses the impact that the paper “Decoupling of the minority PhD talent pool and assistant professor hiring
Michael D. L. Johnson
doaj   +1 more source

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