Results 91 to 100 of about 285,743 (339)

Just a Fad? Gamification in Health and Fitness Apps

open access: yesJMIR Serious Games, 2014
Background Gamification has been a predominant focus of the health app industry in recent years. However, to our knowledge, there has yet to be a review of gamification elements in relation to health behavior constructs, or insight into the true ...
C. Lister   +4 more
semanticscholar   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong   +8 more
wiley   +1 more source

A Gathering For Gardner Puzzle-Game [PDF]

open access: yes, 2017
Each different letter of GATHERING FOR GARDNER is used exactly three times in the following words: DIE, FAD, FIT, FOG, GIN, HAG, HER, HOD, NOR, RAT ...
Farrell, Jeremiah, Morgan, Chris
core   +1 more source

Optical Imaging of Lipopolysaccharide-induced Oxidative Stress in Acute Lung Injury from Hyperoxia and Sepsis [PDF]

open access: yes, 2013
Reactive oxygen species (ROS) have been implicated in the pathogenesis of many acute and chronic pulmonary disorders such as acute lung injury (ALI) in adults and bronchopulmonary dysplasia (BPD) in premature infants.
Audi, Said H.   +6 more
core   +3 more sources

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li   +13 more
wiley   +1 more source

Unifying Scaling Relations and Multiple Reaction Mechanisms for Screening Transition Metal‐Doped Co3O4 for Oxygen Evolution Reaction

open access: yesAngewandte Chemie, EarlyView.
Doped Co3O4 climbs a mechanistic volcano: transition‐metal substitution reshapes the OER activity landscape, while multiple competing reaction mechanisms govern the volcano trends across different dopants. ABSTRACT Accelerating the discovery of oxygen‐evolution reaction (OER) catalysts requires high‐throughput screening strategies combining descriptor ...
Kapil Dhaka   +7 more
wiley   +2 more sources

Human and Organisational Factors: Fad or not Fad? [PDF]

open access: yes, 2020
In this chapter, I take a step back in order to add some elements of discussion by embedding human and organisational factors within a broader historical and sociological context that has so far not been available in the literature. The reason for doing so is that there is a proliferation of various methods, ideas and models in this area.
openaire   +3 more sources

Learning from practice: How HR analytics avoids being a management fad

open access: yes, 2015
Summary Human resource (HR) analytics is touted to have the potential to bring great value to general managers’ and HR leaders’ decision-making on human and organization capital by supplementing intuition and experience with evidence.
Thomas H. Rasmussen, D. Ulrich
semanticscholar   +1 more source

Sensing and Filtering Environmental Fluctuations: The Case of Biomolecular Condensates in Plants

open access: yesAdvanced Science, EarlyView.
The diversity of plant condensates reflects constraints of sessile organisms to coordinate postembryonic development with environmental adaptation. This review examines how plants employ condensates to integrate temperature, light, redox, and nutrient signals.
Panagiotis N. Moschou, Dorothee Staiger
wiley   +1 more source

Mid-infrared microlensing of accretion disc and dusty torus in quasars: effects on flux ratio anomalies [PDF]

open access: yes, 2013
Multiply-imaged quasars and AGNs observed in the mid-infrared (MIR) range are commonly assumed to be unaffected by the microlensing produced by the stars in their lensing galaxy.
Anguita, T.   +4 more
core   +1 more source

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