Results 191 to 200 of about 74,830 (289)

Supervised Protein Structure Classification Using Topological Persistence With DeltaFold

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Recent advances in protein structure prediction have considerably increased the number of available structures, underscoring the need for scalable and accurate methods to compare and classify this huge amount of data. Current approaches based on sequence alignment or structural superposition often lack sensitivity and/or are computationally ...
Joseph Nardin‐Gennequin, Gabriela Ciuperca, Céline Brochier‐Armanet, Philippe Malbos   +3 more
wiley   +1 more source

Transaldolase 1 contributes to pentose phosphate pathway disruption and synaptic dysfunction in Alzheimer's disease. [PDF]

Transl Neurodegener
Hu X, Yu Y, Luo H, Li J, Zhang X, Wang G, Li J, Li J, Chen H, Qiu Y.   +9 more
europepmc   +1 more source

Mortality in an invasive ant does not scale linearly with fipronil exposure

Pest Management Science, EarlyView.
Increasing fipronil concentration did not linearly increase yellow crazy ant mortality when introduced via horizontal transfer; high doses may limit food sharing. Queen mortality was low, and surviving workers were averse to feeding. Abstract Background Controlling eusocial invasive and other pestiferous insects is difficult.
Peter Yeeles, Angela Strain, Lori Lach
wiley   +1 more source

Submicromolar imaging of intrinsic chromophores by two-photon photothermal microscopy captures mitochondrial response to chemotherapy. [PDF]

Sci Adv
Hai N, Dessai CVP, Sun D, Ao J, Lyu PT, Zhu Y, Cheng JX.   +6 more
europepmc   +1 more source

In planta analysis of the mode of action of cinmethylin and confirmation of fatty acyl‐ACP thioesterases (FATs) as primary site of action

Pest Management Science, EarlyView.
In planta analysis of the mode of action of cinmethylin and confirmation of fatty acyl‐ACP thioesterases (FATs) as primary site of action. Cinmethylin inhibits FATs, disrupting eukaryotic de novo lipid biosynthesis and causing defects in cell division, elongation and integrity. We confirm FATs as the primary site of action in planta.
Maximillian Pollmeier, Aisha Gerhardt, Janneke Hendriks, Katharina Kaprocki, Alexandra Zimmermann, Sarina Ruehm, Martina Marnet, Maria Stroe, Jorge Alfredo Rojas Biava, Clara Hofmann, Michael Betz, Sascha Schlaefer, Philipp Ternes, Jens Lerchl, Selene Garcia‐Hernandez, Philipp Johnen   +15 more
wiley   +1 more source

Diversity of electron-bifurcating CO₂-fixing supercomplexes in methanogens. [PDF]

Sci Adv
Segundo-Acosta PS, Nomura S, Fernandes-Queiroz JP, Protasov E, Kahnt J, Kaneko M, Hochberg G, Shima S, Murphy BJ.   +8 more
europepmc   +1 more source

Multi‐Platform Deployments of Low‐Cost Devices for Cetacean Passive Acoustic Monitoring

Remote Sensing in Ecology and Conservation, EarlyView.
Recent advances in affordable, user‐friendly devices offer new opportunities to overcome cost constraints of underwater passive acoustic monitoring (PAM) and expand acoustic data collection. In this study, we deployed low‐cost acoustic recorders and underwater cameras across a range of platforms in the Western Mediterranean, including fishing gear ...
Greta Jankauskaite, François Poisson, Irati Abascal, Javier Menéndez‐Blázquez, Clara Cánovas Pérez, Sofia Conti, Ricardo Sagarminaga, Juan Antonio Raga, David March   +8 more
wiley   +1 more source

Structural basis of ligand selectivity in FAD/NAD(P)H-dependent dehydrogenases: insights from trypanothione reductase and type II NADH dehydrogenase. [PDF]

Protein Sci
Perrone GCM, Spadone S, Francavilla AL, Morselli S, Todisco S, Ortalli M, Mendoza-Roldan JA, Scaglione V, Sgobba MN, Guerra L, Belluti F, Varani S, Otranto D, De Grassi A, Volpicella M, Pierri CL.   +15 more
europepmc   +1 more source

A Hero's Journey to Systemic Change: Developing Expertise in Agricultural Development

Sustainable Development, EarlyView.
ABSTRACT Experts in rural development and agrarian change wield considerable influence over programme design and delivery, directing resources and shaping trajectories towards the Sustainable Development Goals (SDGs). Yet the pathways through which such expertise develops remain under‐examined. This study examines the journey to expertise among experts
Kirt Hainzer, Caitlin Finlayson, Nicholas Harrigan, Andrew McGregor, Katharine McKinnon, Van Touch, Ariane Utomo, Brian R. Cook   +7 more
wiley   +1 more source

Combinatorial metabolic engineering of <i>Mycobacterium neoaurum</i> LY-2 for efficient androstenedione production from phytosterols. [PDF]

Synth Syst Biotechnol
Xu L, Peng C, Pan W, Tong Y, Shi J, Xu Z, Li H.   +6 more
europepmc   +1 more source