Results 41 to 50 of about 130,979 (278)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Closed-form Distribution and Analysis of a Combined Nakagami-lognormal Shadowing and Unshadowing Fading Channel

Journal of Telecommunications and Information Technology, 2016
The realistic wireless channels face combined (time shared) Nakagami-lognormal shadowing and unshadowing fading because of time varying nature of radio channel and mobile user.
Rupender Singh, Meenakshi Rawat
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

On multipath fading channels at high SNR [PDF]

2008 IEEE International Symposium on Information Theory, 2008
This paper studies the capacity of discrete-time multipath fading channels. It is assumed that the number of paths is finite, i.e., that the channel output is influenced by the present and by the L previous channel inputs. A noncoherent channel model is considered where neither transmitter nor receiver are cognizant of the fading's realization, but ...
Tobias Koch 0001, Amos Lapidoth
openaire   +5 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Improved Pilot-Aided Channel Estimation for MIMO-OFDM Fading Channels

International Journal of Antennas and Propagation, 2013
An improved pilot-aided channel estimation scheme is proposed to enhance the channel estimation accuracy of multiple-input multiple-output-orthogonal frequency division multiplexing (MIMO-OFDM) fading channels. Based on the adaptive path number selection
J. Mar, Chi-Cheng Kuo, M. B. Basnet
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

New spectrum sensing method under time-variant flat fading channels

Tongxin xuebao, 2014
A dynamic state-space model (DSM) was presented for the problem of spectrum sensing under time-variant flat fading channels (TVFF).The primary user (PU) state and the fading channel were characterized as hidden states.On this basis,a novel method was ...
Meng-wei SUN, Long ZHAO, Qiao-chun XU, Bin LI, Cheng-lin ZHAO   +4 more
doaj   +2 more sources

Space-Time Turbo Trellis Coded Modulation for Wireless Data Communications

EURASIP Journal on Advances in Signal Processing, 2002
This paper presents the design of space-time turbo trellis coded modulation (ST turbo TCM) for improving the bandwidth efficiency and the reliability of future wireless data networks.
Welly Firmanto, Branka Vucetic, Jinhong Yuan, Zhuo Chen   +3 more
doaj   +1 more source